STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG5521Probable Rho GTPase-activating protein CG5521; GTPase activator activity. It is involved in the biological process described with: regulation of small GTPase mediated signal transduction; positive regulation of GTPase activity. (1964 aa)    
Predicted Functional Partners:
CG4467
Uncharacterized protein, isoform B; Metalloaminopeptidase activity; zinc ion binding; peptide binding. It is involved in the biological process described with: peptide catabolic process; proteolysis.
      
 0.790
kappaB-Ras
NF-kappa-B inhibitor-interacting Ras-like protein; Atypical Ras-like protein that may act as a regulator of NF- kappa-B activity, possibly by preventing the degradation of NF-kappa-B inhibitor cactus; Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.
    
 
 0.749
CG34408
Uncharacterized protein, isoform H; GTPase activator activity. It is involved in the biological process described with: regulation of small GTPase mediated signal transduction; activation of GTPase activity.
   
 
0.692
CG13175
GEO13458p1.
      
 0.680
CG30159
GH17623p.
      
 0.680
CG34347
Uncharacterized protein, isoform B.
   
  
 0.674
CG33964
GM20958p.
   
  
 0.672
Tsp42Ea
Tetraspanin.
      
 0.670
CG15270
Anoctamin; Intracellular calcium activated chloride channel activity; calcium activated cation channel activity. It is involved in the biological process described with: chloride transport; cation transport; transmembrane transport.
      
 0.669
CG43980
Uncharacterized protein, isoform C; Protein heterodimerization activity.
      
 0.669
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.