STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Nlg4Neuroligin 4 (Nlg4) encodes a synaptic adhesion molecule involved in synapse formation and synaptic transmission. (1281 aa)    
Predicted Functional Partners:
Est-P
Esterase P; Carboxylic ester hydrolase activity; Belongs to the type-B carboxylesterase/lipase family.
  
  
 
0.920
Est-6
Esterase-6; Transferred from the ejaculatory bulbs of males to the female genitals upon copulation, plays an important role in the reproductive biology.
  
  
 
0.920
betaGlu
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.
    
 0.902
CG15117
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.
    
 0.902
CG8349
CMP/dCMP-type deaminase domain-containing protein; Cytidine deaminase activity; zinc ion binding. It is involved in the biological process described with: cytidine deamination.
     
  0.900
CG8360
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
     
  0.900
CG8353
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
     
  0.900
Nrx-1
Neurexin 1, isoform F; Neurexin 1 (Nrx-1) encodes a transmembrane synaptic adhesive molecule that regulates the synaptic architecture and function in the brain and neuromuscular junction. It contributes to synaptic growth, transmission, synaptic formation and also regulation of learning and memory, locomotion and visual function.
    
 
 0.889
Ugt37A2
UDP-glycosyltransferase family 37 member A2; UDP-glycosyltransferase activity; transferase activity, transferring hexosyl groups.
     
 0.790
Ugt49B1
UDP-glucuronosyltransferase; Transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity. It is involved in the biological process described with: UDP-glucose metabolic process; Belongs to the UDP-glycosyltransferase family.
     
  0.650
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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