Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Max | Mnt | FBpp0311541 | FBpp0298278 | Max (Max) encodes a member of the basic-helix-loop-helix-zipper family of transcription factors. It specifically forms heterodimers with the products of Myc and Mnt enabling the binding and transcriptional activity of the heterodimeric complex, which regulate genes involved in cell and organismal growth. | Mnt, isoform I; Mnt (Mnt) encodes a protein that belongs to the basic-helic-loop-helix-zipper class of transcription factors, which form heterodimers with the protein encoded by Max. Mnt product acts as a repressor of transcription by recruiting a co-repressor complex to its genomic binding sites. It antagonizes cell growth promoting functions of the product encoded by Myc and its depletion produces flies with larger cells, increased weight, and decreased lifespan. | 0.962 |
| Max | Mondo | FBpp0311541 | FBpp0290674 | Max (Max) encodes a member of the basic-helix-loop-helix-zipper family of transcription factors. It specifically forms heterodimers with the products of Myc and Mnt enabling the binding and transcriptional activity of the heterodimeric complex, which regulate genes involved in cell and organismal growth. | Mlx interactor alpha; Mondo (Mondo) encodes a basic helix-loop-helix-leucine zipper transcription factor involved in lipid and carbohydrate metabolism. Together with its binding partner encoded by bigmax, it controls sugar-dependent gene expression, including activation of genes involved in lipogenesis. Mondo mutants are intolerant to dietary sugars and have impaired muscle function. | 0.589 |
| Max | Myc | FBpp0311541 | FBpp0303995 | Max (Max) encodes a member of the basic-helix-loop-helix-zipper family of transcription factors. It specifically forms heterodimers with the products of Myc and Mnt enabling the binding and transcriptional activity of the heterodimeric complex, which regulate genes involved in cell and organismal growth. | Myc protein; Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence CAC[GA]TG. Seems to activate the transcription of growth-related genes; required for cellular proliferation and growth. Functions in the TORC2-mediated regulation of cell growth, acting downstream of the TORC2 complex. Inhibits the demethylase activity of Lid. Activates transcription of mbm. Has a role in ribosome biogenesis and endoreplication in fat body cells by activating the transcription of LTV1. Able to induce the SCF E3 ubiqui [...] | 0.983 |
| Max | Sin3A | FBpp0311541 | FBpp0293225 | Max (Max) encodes a member of the basic-helix-loop-helix-zipper family of transcription factors. It specifically forms heterodimers with the products of Myc and Mnt enabling the binding and transcriptional activity of the heterodimeric complex, which regulate genes involved in cell and organismal growth. | Sin3A, isoform G; Sin3A (Sin3A) encodes a chromatin regulator with roles during muscle development, cell migration and Wnt signalling regulation. | 0.698 |
| Max | Usf | FBpp0311541 | FBpp0301043 | Max (Max) encodes a member of the basic-helix-loop-helix-zipper family of transcription factors. It specifically forms heterodimers with the products of Myc and Mnt enabling the binding and transcriptional activity of the heterodimeric complex, which regulate genes involved in cell and organismal growth. | Usf, isoform B; Usf (Usf) encodes a bHLH family transcription factor that recognizes E-boxes in the Ste promoter. | 0.562 |
| Mnt | Max | FBpp0298278 | FBpp0311541 | Mnt, isoform I; Mnt (Mnt) encodes a protein that belongs to the basic-helic-loop-helix-zipper class of transcription factors, which form heterodimers with the protein encoded by Max. Mnt product acts as a repressor of transcription by recruiting a co-repressor complex to its genomic binding sites. It antagonizes cell growth promoting functions of the product encoded by Myc and its depletion produces flies with larger cells, increased weight, and decreased lifespan. | Max (Max) encodes a member of the basic-helix-loop-helix-zipper family of transcription factors. It specifically forms heterodimers with the products of Myc and Mnt enabling the binding and transcriptional activity of the heterodimeric complex, which regulate genes involved in cell and organismal growth. | 0.962 |
| Mnt | Mondo | FBpp0298278 | FBpp0290674 | Mnt, isoform I; Mnt (Mnt) encodes a protein that belongs to the basic-helic-loop-helix-zipper class of transcription factors, which form heterodimers with the protein encoded by Max. Mnt product acts as a repressor of transcription by recruiting a co-repressor complex to its genomic binding sites. It antagonizes cell growth promoting functions of the product encoded by Myc and its depletion produces flies with larger cells, increased weight, and decreased lifespan. | Mlx interactor alpha; Mondo (Mondo) encodes a basic helix-loop-helix-leucine zipper transcription factor involved in lipid and carbohydrate metabolism. Together with its binding partner encoded by bigmax, it controls sugar-dependent gene expression, including activation of genes involved in lipogenesis. Mondo mutants are intolerant to dietary sugars and have impaired muscle function. | 0.661 |
| Mnt | Myc | FBpp0298278 | FBpp0303995 | Mnt, isoform I; Mnt (Mnt) encodes a protein that belongs to the basic-helic-loop-helix-zipper class of transcription factors, which form heterodimers with the protein encoded by Max. Mnt product acts as a repressor of transcription by recruiting a co-repressor complex to its genomic binding sites. It antagonizes cell growth promoting functions of the product encoded by Myc and its depletion produces flies with larger cells, increased weight, and decreased lifespan. | Myc protein; Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence CAC[GA]TG. Seems to activate the transcription of growth-related genes; required for cellular proliferation and growth. Functions in the TORC2-mediated regulation of cell growth, acting downstream of the TORC2 complex. Inhibits the demethylase activity of Lid. Activates transcription of mbm. Has a role in ribosome biogenesis and endoreplication in fat body cells by activating the transcription of LTV1. Able to induce the SCF E3 ubiqui [...] | 0.786 |
| Mnt | Rab40 | FBpp0298278 | FBpp0073502 | Mnt, isoform I; Mnt (Mnt) encodes a protein that belongs to the basic-helic-loop-helix-zipper class of transcription factors, which form heterodimers with the protein encoded by Max. Mnt product acts as a repressor of transcription by recruiting a co-repressor complex to its genomic binding sites. It antagonizes cell growth promoting functions of the product encoded by Myc and its depletion produces flies with larger cells, increased weight, and decreased lifespan. | Rab40, isoform B; GTP binding; GTPase activity. It is involved in the biological process described with: protein localization to plasma membrane; vesicle-mediated transport; Rab protein signal transduction; intracellular protein transport. | 0.677 |
| Mnt | Sin3A | FBpp0298278 | FBpp0293225 | Mnt, isoform I; Mnt (Mnt) encodes a protein that belongs to the basic-helic-loop-helix-zipper class of transcription factors, which form heterodimers with the protein encoded by Max. Mnt product acts as a repressor of transcription by recruiting a co-repressor complex to its genomic binding sites. It antagonizes cell growth promoting functions of the product encoded by Myc and its depletion produces flies with larger cells, increased weight, and decreased lifespan. | Sin3A, isoform G; Sin3A (Sin3A) encodes a chromatin regulator with roles during muscle development, cell migration and Wnt signalling regulation. | 0.881 |
| Mnt | Usf | FBpp0298278 | FBpp0301043 | Mnt, isoform I; Mnt (Mnt) encodes a protein that belongs to the basic-helic-loop-helix-zipper class of transcription factors, which form heterodimers with the protein encoded by Max. Mnt product acts as a repressor of transcription by recruiting a co-repressor complex to its genomic binding sites. It antagonizes cell growth promoting functions of the product encoded by Myc and its depletion produces flies with larger cells, increased weight, and decreased lifespan. | Usf, isoform B; Usf (Usf) encodes a bHLH family transcription factor that recognizes E-boxes in the Ste promoter. | 0.748 |
| Mnt | bigmax | FBpp0298278 | FBpp0084543 | Mnt, isoform I; Mnt (Mnt) encodes a protein that belongs to the basic-helic-loop-helix-zipper class of transcription factors, which form heterodimers with the protein encoded by Max. Mnt product acts as a repressor of transcription by recruiting a co-repressor complex to its genomic binding sites. It antagonizes cell growth promoting functions of the product encoded by Myc and its depletion produces flies with larger cells, increased weight, and decreased lifespan. | GM14426p; Bigmax (bigmax) encodes a basic helix-loop-helix-leucine zipper transcription factor. Together with its binding partner encoded by Mondo, the product of bigmax is involved in sugar-dependent gene regulation. It is involved in transcriptional control of many metabolic pathways, including glycolysis, de novo lipogenesis and the pentose phosphate pathway. Loss of bigmax function produces dietary sugar intolerance. | 0.671 |
| Mnt | foxo | FBpp0298278 | FBpp0293589 | Mnt, isoform I; Mnt (Mnt) encodes a protein that belongs to the basic-helic-loop-helix-zipper class of transcription factors, which form heterodimers with the protein encoded by Max. Mnt product acts as a repressor of transcription by recruiting a co-repressor complex to its genomic binding sites. It antagonizes cell growth promoting functions of the product encoded by Myc and its depletion produces flies with larger cells, increased weight, and decreased lifespan. | Forkhead box protein O; Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thord4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor. Foxo activated in the adult fat body can regulate lifespan in adults; an insulin peptide itself m [...] | 0.677 |
| Mnt | lid | FBpp0298278 | FBpp0311492 | Mnt, isoform I; Mnt (Mnt) encodes a protein that belongs to the basic-helic-loop-helix-zipper class of transcription factors, which form heterodimers with the protein encoded by Max. Mnt product acts as a repressor of transcription by recruiting a co-repressor complex to its genomic binding sites. It antagonizes cell growth promoting functions of the product encoded by Myc and its depletion produces flies with larger cells, increased weight, and decreased lifespan. | Lysine-specific demethylase lid; Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Specifically demethylates trimethylated H3 'Lys-4'. Required for the correct regulation of homeotic genes during development. Plays a role in the regulation of the circadian rhythm and in maintaining the normal periodicity of the circadian clock. Regulates the expression of clock-controlled genes including tim, per and cry. | 0.670 |
| Mnt | mbt | FBpp0298278 | FBpp0074060 | Mnt, isoform I; Mnt (Mnt) encodes a protein that belongs to the basic-helic-loop-helix-zipper class of transcription factors, which form heterodimers with the protein encoded by Max. Mnt product acts as a repressor of transcription by recruiting a co-repressor complex to its genomic binding sites. It antagonizes cell growth promoting functions of the product encoded by Myc and its depletion produces flies with larger cells, increased weight, and decreased lifespan. | Serine/threonine-protein kinase PAK mbt; Involved in neurogenesis of the adult central nervous system, and together with Cdc42, regulates photoreceptor cell morphogenesis. Phosphorylates exogenous substrates when activated by Cdc42. | 0.665 |
| Mondo | Max | FBpp0290674 | FBpp0311541 | Mlx interactor alpha; Mondo (Mondo) encodes a basic helix-loop-helix-leucine zipper transcription factor involved in lipid and carbohydrate metabolism. Together with its binding partner encoded by bigmax, it controls sugar-dependent gene expression, including activation of genes involved in lipogenesis. Mondo mutants are intolerant to dietary sugars and have impaired muscle function. | Max (Max) encodes a member of the basic-helix-loop-helix-zipper family of transcription factors. It specifically forms heterodimers with the products of Myc and Mnt enabling the binding and transcriptional activity of the heterodimeric complex, which regulate genes involved in cell and organismal growth. | 0.589 |
| Mondo | Mnt | FBpp0290674 | FBpp0298278 | Mlx interactor alpha; Mondo (Mondo) encodes a basic helix-loop-helix-leucine zipper transcription factor involved in lipid and carbohydrate metabolism. Together with its binding partner encoded by bigmax, it controls sugar-dependent gene expression, including activation of genes involved in lipogenesis. Mondo mutants are intolerant to dietary sugars and have impaired muscle function. | Mnt, isoform I; Mnt (Mnt) encodes a protein that belongs to the basic-helic-loop-helix-zipper class of transcription factors, which form heterodimers with the protein encoded by Max. Mnt product acts as a repressor of transcription by recruiting a co-repressor complex to its genomic binding sites. It antagonizes cell growth promoting functions of the product encoded by Myc and its depletion produces flies with larger cells, increased weight, and decreased lifespan. | 0.661 |
| Mondo | Myc | FBpp0290674 | FBpp0303995 | Mlx interactor alpha; Mondo (Mondo) encodes a basic helix-loop-helix-leucine zipper transcription factor involved in lipid and carbohydrate metabolism. Together with its binding partner encoded by bigmax, it controls sugar-dependent gene expression, including activation of genes involved in lipogenesis. Mondo mutants are intolerant to dietary sugars and have impaired muscle function. | Myc protein; Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence CAC[GA]TG. Seems to activate the transcription of growth-related genes; required for cellular proliferation and growth. Functions in the TORC2-mediated regulation of cell growth, acting downstream of the TORC2 complex. Inhibits the demethylase activity of Lid. Activates transcription of mbm. Has a role in ribosome biogenesis and endoreplication in fat body cells by activating the transcription of LTV1. Able to induce the SCF E3 ubiqui [...] | 0.596 |
| Mondo | Sin3A | FBpp0290674 | FBpp0293225 | Mlx interactor alpha; Mondo (Mondo) encodes a basic helix-loop-helix-leucine zipper transcription factor involved in lipid and carbohydrate metabolism. Together with its binding partner encoded by bigmax, it controls sugar-dependent gene expression, including activation of genes involved in lipogenesis. Mondo mutants are intolerant to dietary sugars and have impaired muscle function. | Sin3A, isoform G; Sin3A (Sin3A) encodes a chromatin regulator with roles during muscle development, cell migration and Wnt signalling regulation. | 0.413 |
| Mondo | Usf | FBpp0290674 | FBpp0301043 | Mlx interactor alpha; Mondo (Mondo) encodes a basic helix-loop-helix-leucine zipper transcription factor involved in lipid and carbohydrate metabolism. Together with its binding partner encoded by bigmax, it controls sugar-dependent gene expression, including activation of genes involved in lipogenesis. Mondo mutants are intolerant to dietary sugars and have impaired muscle function. | Usf, isoform B; Usf (Usf) encodes a bHLH family transcription factor that recognizes E-boxes in the Ste promoter. | 0.604 |
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