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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtTFB1Dimethyladenosine transferase 1, mitochondrial; Probable S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. In contrast to mtTFB2, it does not have a critical role in either transcription or regulation of the copy number of mitochondrial DNA. (330 aa)    
Predicted Functional Partners:
mtRNApol
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.
   
 
 0.996
CG32533
LD31543p; RNA binding; helicase activity. It is involved in the biological process described with: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.
  
 
 0.982
bys
Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits; Belongs to the bystin family.
   
 
 0.976
Tsr1
Pre-rRNA-processing protein TSR1 homolog; Required during maturation of the 40S ribosomal subunit in the nucleolus; Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.
   
 
 0.952
CG12325
LD10780p; It is involved in the biological process described with: ribosomal small subunit assembly; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA).
   
 
 0.948
RpS11
40S ribosomal protein S11; Structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the universal ribosomal protein uS17 family.
  
 
 0.930
RpS18
Ribosomal protein S18 (RpS18) encodes a ribosomal protein located at the top of the head of the 40S subunit and contacts several helices of the 18S rRNA.
    
 
 0.924
CG11920
FI08810p; snoRNA binding. It is involved in the biological process described with: rRNA processing.
   
   0.920
Ccdc56
Cytochrome c oxidase assembly factor 3, mitochondrial; Coiled-coil domain containing 56 (Ccdc56) encodes a small mitochondrial protein required for cytochrome c oxidase assembly and function; Belongs to the COA3 family.
 
 
 
 0.920
CG8064
GH01043p; snoRNA binding. It is involved in the biological process described with: maturation of SSU-rRNA.
   
   0.918
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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