STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TuspTusp, isoform F; Tusp (Tusp) encodes a protein involved in SNARE complex assembly; Belongs to the TUB family. (1433 aa)    
Predicted Functional Partners:
CG31869
Uncharacterized protein, isoform A.
   
  
 0.674
Rim
Rab3 interacting molecule (Rim) encodes a scaffolding protein at the synaptic active zone, with important roles in promoting neurotransmitter release.
   
  
 0.671
CG15212
GEO09627p1.
      
 0.669
CG4000
GH21518p.
      
 0.669
CG31086
Uncharacterized protein, isoform A.
      
 0.669
Tb
RE61793p; Structural constituent of chitin-based cuticle. It is involved in the biological process described with: chitin-based cuticle development; body morphogenesis.
      
 0.666
GluProRS
Bifunctional glutamate/proline--tRNA ligase; Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
      
 0.662
CG10383
LD21810p; CG10383 encodes a hydrolase involved in the regulation of glycosylphosphatidylinositol metabolism, determination of lifespan and sleep.
      
 0.613
kel
Ring canal kelch protein; Kelch (kel) encodes a substrate targeting component of a Cullin3-RING ubiquitin E3 ligase. It binds F-actin in vitro, while its predominant in vivo function is in the ubiquitin-proteasome pathway. It has an essential role in oogenesis, where it is required for cytoskeletal organization in ovarian ring canals.
     
 0.610
CG11699
CG11699-RA protein.
      
 0.609
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.