STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG42700Uncharacterized protein, isoform I. (509 aa)    
Predicted Functional Partners:
CG18265
GH10077p; Nucleic acid binding.
    
 
 0.914
CG7720
GH20226p; Symporter activity. It is involved in the biological process described with: transmembrane transport; sodium ion transport; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
      
 0.911
CG9813
Uncharacterized protein, isoform G.
   
  
 0.841
Sp212
Serine-peptidase 212; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; response to bacterium; response to fungus.
    
 
 0.837
CG34351
Uncharacterized protein, isoform D.
   
  
 0.837
CG7329
Uncharacterized protein, isoform A.
      
 0.836
crol
Crooked legs (crol) encodes a zinc finger transcription factor induced by 20-hydroxyecdysone at the onset of metamorphosis. It regulates wg transcription and cell cycle progression in the wing. Its over-expression in the eye accelerates the cell cycle and de-represses silenced genes.
    
 
 0.614
bdg
Bedraggled, isoform A; Bedraggled (bdg) encodes a putative transporter involved in the fate commitment of the R3/R4 pair of photoreceptor cells.
  
     0.500
CG31326
Peptidase S1 domain-containing protein; It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
    
 
 0.499
Crtc
CREB-regulated transcription coactivator (Crtc) encodes a highly conserved transcriptional coactivator of cAMP-response element-binding protein (CREB). Its nuclear localization is regulated by several factors including intracellular cAMP or calcium levels, or calcineurin. Sik family kinases also phosphorylate to inhibit the product of Crtc and, consequently, control energy homeostais and lipid metabolism.
      
 0.491
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.