STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Spase22-23Signal peptidase complex subunit 3; Component of the microsomal signal peptidase complex which removes signal peptides and other N-terminal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. (179 aa)    
Predicted Functional Partners:
Spase25
Signal peptidase complex subunit 2; Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.
   
 0.996
twr
Signal peptidase complex catalytic subunit SEC11; Serine-type peptidase activity; peptidase activity. It is involved in the biological process described with: signal peptide processing.
   
 0.988
Spase12
Signal peptidase complex subunit 1; Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.
   
 0.988
CG16734
Uncharacterized protein.
    
 
 0.914
CG8642
Fibrinogen C-terminal domain-containing protein; Chitin binding; G protein-coupled receptor binding. It is involved in the biological process described with: G protein-coupled receptor signaling pathway.
      
 0.838
CG2839
C-type lectin domain-containing protein; Signaling receptor activity.
   
 
 0.799
CG13587
C-type lectin domain-containing protein.
    
 
 0.798
CG43797
C-type lectin domain-containing protein.
    
 
 0.798
CG14499
C-type lectin domain-containing protein; Carbohydrate binding.
    
 
 0.798
CG9500
Fibrinogen C-terminal domain-containing protein.
      
 0.791
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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