node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CanA-14F | CanA1 | FBpp0293728 | FBpp0306613 | Serine/threonine-protein phosphatase 2B catalytic subunit 3; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. | Serine/threonine-protein phosphatase 2B catalytic subunit 1; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin; Belongs to the PPP phosphatase family. PP-2B subfamily. | 0.937 |
CanA-14F | CanB | FBpp0293728 | FBpp0070731 | Serine/threonine-protein phosphatase 2B catalytic subunit 3; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. | Calcineurin subunit B type 1; Calcineurin is a calcium-binding and calmodulin-binding protein found in all cells from yeast to mammals, and a calcium- dependent, calmodulin-stimulated protein phosphatase. | 0.997 |
CanA-14F | CanB2 | FBpp0293728 | FBpp0301600 | Serine/threonine-protein phosphatase 2B catalytic subunit 3; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. | Calcineurin subunit B type 2; Calcineurin is a calcium-binding and calmodulin-binding protein found in all cells from yeast to mammals, and a calcium- dependent, calmodulin-stimulated protein phosphatase. | 0.989 |
CanA-14F | Fkbp12 | FBpp0293728 | FBpp0085703 | Serine/threonine-protein phosphatase 2B catalytic subunit 3; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. | 12 kDa FK506-binding protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Binds to ligand-free TGF beta type I receptor, from which it is released upon a ligand-induced, type II receptor mediated phosphorylation of the type I receptor. Binding is inhibitory to the signaling pathways of the TGF beta family ligands. | 0.849 |
CanA-14F | PPP4R2r | FBpp0293728 | FBpp0071386 | Serine/threonine-protein phosphatase 2B catalytic subunit 3; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. | Serine/threonine-protein phosphatase 4 regulatory subunit 2; Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4) (By similarity). The probable PP4 complex Pp4-19C-PPP4R2r-flfl (PPP4C-PPP4R2-PPP4R3) is required to prevent caspase induced cell death (in vitro). | 0.801 |
CanA-14F | Plc21C | FBpp0293728 | FBpp0089226 | Serine/threonine-protein phosphatase 2B catalytic subunit 3; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.904 |
CanA-14F | Pp2A-29B | FBpp0293728 | FBpp0308836 | Serine/threonine-protein phosphatase 2B catalytic subunit 3; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. | Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit; Protein phosphatase 2A at 29B (Pp2A-29B) encodes the structural A subunit of the trimeric PP2A phosphatase enzyme. It links the catalytic C subunit encoded by mts and a variable regulatory B family subunit, which directs the enzyme to distinct substrates. The roles of Pp2A-29B product include centriole duplication, chromosome segregation, autophagy, axonal transport, growth regulation, and active zone stabilization. | 0.804 |
CanA-14F | Pp2B-14D | FBpp0293728 | FBpp0301546 | Serine/threonine-protein phosphatase 2B catalytic subunit 3; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. | Serine/threonine-protein phosphatase 2B catalytic subunit 2; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin; Belongs to the PPP phosphatase family. PP-2B subfamily. | 0.913 |
CanA-14F | norpA | FBpp0293728 | FBpp0290690 | Serine/threonine-protein phosphatase 2B catalytic subunit 3; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (By similarity). Essential component of the phototransduction pathway. Essential downstream component of a hh-signaling pathway which regulates the Duox-dependent gut immune response to bacterial uracil; required for the activation of Cad99C and consequently Cad99C-dependent endosome formation, which is essential for the Duox-dependent product [...] | 0.914 |
CanA-14F | sra | FBpp0293728 | FBpp0310844 | Serine/threonine-protein phosphatase 2B catalytic subunit 3; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. | Protein sarah; Required for elongation of meiosis I spindle. Critical for ovulation, meiotic progression in oocytes and female courtship behavior, including their postmating changes. Regulates female meiosis by controlling calcineurin activity in the germline. Has a role in calcium signaling during egg activation; bcd mRNA polyadenylation and translation in the oocyte. Belongs to the RCAN family. | 0.896 |
CanA1 | CanA-14F | FBpp0306613 | FBpp0293728 | Serine/threonine-protein phosphatase 2B catalytic subunit 1; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin; Belongs to the PPP phosphatase family. PP-2B subfamily. | Serine/threonine-protein phosphatase 2B catalytic subunit 3; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. | 0.937 |
CanA1 | CanB | FBpp0306613 | FBpp0070731 | Serine/threonine-protein phosphatase 2B catalytic subunit 1; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin; Belongs to the PPP phosphatase family. PP-2B subfamily. | Calcineurin subunit B type 1; Calcineurin is a calcium-binding and calmodulin-binding protein found in all cells from yeast to mammals, and a calcium- dependent, calmodulin-stimulated protein phosphatase. | 0.997 |
CanA1 | CanB2 | FBpp0306613 | FBpp0301600 | Serine/threonine-protein phosphatase 2B catalytic subunit 1; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin; Belongs to the PPP phosphatase family. PP-2B subfamily. | Calcineurin subunit B type 2; Calcineurin is a calcium-binding and calmodulin-binding protein found in all cells from yeast to mammals, and a calcium- dependent, calmodulin-stimulated protein phosphatase. | 0.982 |
CanA1 | Fkbp12 | FBpp0306613 | FBpp0085703 | Serine/threonine-protein phosphatase 2B catalytic subunit 1; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin; Belongs to the PPP phosphatase family. PP-2B subfamily. | 12 kDa FK506-binding protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Binds to ligand-free TGF beta type I receptor, from which it is released upon a ligand-induced, type II receptor mediated phosphorylation of the type I receptor. Binding is inhibitory to the signaling pathways of the TGF beta family ligands. | 0.860 |
CanA1 | PPP4R2r | FBpp0306613 | FBpp0071386 | Serine/threonine-protein phosphatase 2B catalytic subunit 1; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin; Belongs to the PPP phosphatase family. PP-2B subfamily. | Serine/threonine-protein phosphatase 4 regulatory subunit 2; Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4) (By similarity). The probable PP4 complex Pp4-19C-PPP4R2r-flfl (PPP4C-PPP4R2-PPP4R3) is required to prevent caspase induced cell death (in vitro). | 0.866 |
CanA1 | Plc21C | FBpp0306613 | FBpp0089226 | Serine/threonine-protein phosphatase 2B catalytic subunit 1; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin; Belongs to the PPP phosphatase family. PP-2B subfamily. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.903 |
CanA1 | Pp2A-29B | FBpp0306613 | FBpp0308836 | Serine/threonine-protein phosphatase 2B catalytic subunit 1; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin; Belongs to the PPP phosphatase family. PP-2B subfamily. | Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit; Protein phosphatase 2A at 29B (Pp2A-29B) encodes the structural A subunit of the trimeric PP2A phosphatase enzyme. It links the catalytic C subunit encoded by mts and a variable regulatory B family subunit, which directs the enzyme to distinct substrates. The roles of Pp2A-29B product include centriole duplication, chromosome segregation, autophagy, axonal transport, growth regulation, and active zone stabilization. | 0.896 |
CanA1 | Pp2B-14D | FBpp0306613 | FBpp0301546 | Serine/threonine-protein phosphatase 2B catalytic subunit 1; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin; Belongs to the PPP phosphatase family. PP-2B subfamily. | Serine/threonine-protein phosphatase 2B catalytic subunit 2; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin; Belongs to the PPP phosphatase family. PP-2B subfamily. | 0.970 |
CanA1 | norpA | FBpp0306613 | FBpp0290690 | Serine/threonine-protein phosphatase 2B catalytic subunit 1; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin; Belongs to the PPP phosphatase family. PP-2B subfamily. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (By similarity). Essential component of the phototransduction pathway. Essential downstream component of a hh-signaling pathway which regulates the Duox-dependent gut immune response to bacterial uracil; required for the activation of Cad99C and consequently Cad99C-dependent endosome formation, which is essential for the Duox-dependent product [...] | 0.910 |
CanA1 | sra | FBpp0306613 | FBpp0310844 | Serine/threonine-protein phosphatase 2B catalytic subunit 1; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin; Belongs to the PPP phosphatase family. PP-2B subfamily. | Protein sarah; Required for elongation of meiosis I spindle. Critical for ovulation, meiotic progression in oocytes and female courtship behavior, including their postmating changes. Regulates female meiosis by controlling calcineurin activity in the germline. Has a role in calcium signaling during egg activation; bcd mRNA polyadenylation and translation in the oocyte. Belongs to the RCAN family. | 0.814 |