STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CG9391Inositol-1-monophosphatase; Inositol monophosphate 1-phosphatase activity. It is involved in the biological process described with: phosphatidylinositol phosphorylation; inositol phosphate dephosphorylation; inositol metabolic process; signal transduction. (278 aa)    
Predicted Functional Partners:
Ipp
Inositol polyphosphate 1-phosphatase (Ipp) encodes a protein involved in synaptic transmission and inositol metabolism regulation.
  
 
 0.966
Inos
Inositol-3-phosphate synthase activity. It is involved in the biological process described with: inositol biosynthetic process; phospholipid biosynthetic process.
  
 
 0.931
Pis
CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content (By similarity). The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme (By similarity). Required for the regeneration of the signaling molecule phosphatidylinositol 4,5- bisphosphate (PtdInsP2) from phosphatidic acid (PA) and maintenance of its steady supply during signaling, thus playing [...]
  
 
 0.930
CG6910
RH44796p; Inositol oxygenase activity; iron ion binding. It is involved in the biological process described with: oxidation-reduction process; inositol catabolic process.
     
 0.912
CG42271
Uncharacterized protein, isoform C; Phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity.
   
 
  0.901
CG15743
Inositol-1,4-bisphosphate 1-phosphatase activity; 3'-nucleotidase activity; inositol monophosphate 1-phosphatase activity. It is involved in the biological process described with: signal transduction; dephosphorylation; phosphate-containing compound metabolic process; phosphatidylinositol phosphorylation; phosphatidylinositol biosynthetic process.
    
 0.743
mRpS34
Mitochondrial ribosomal protein S34; Structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation.
  
  
 0.719
norpA
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (By similarity). Essential component of the phototransduction pathway. Essential downstream component of a hh-signaling pathway which regulates the Duox-dependent gut immune response to bacterial uracil; required for the activation of Cad99C and consequently Cad99C-dependent endosome formation, which is essential for the Duox-dependent product [...]
     
 0.693
CG17026
Inositol-1-monophosphatase; Inositol monophosphate 1-phosphatase activity. It is involved in the biological process described with: inositol metabolic process; signal transduction; inositol phosphate dephosphorylation; phosphatidylinositol phosphorylation.
  
  
 
0.679
CG17027
Inositol-1-monophosphatase; Inositol monophosphate 1-phosphatase activity. It is involved in the biological process described with: signal transduction; inositol metabolic process; inositol phosphate dephosphorylation; phosphatidylinositol phosphorylation.
  
  
 
0.675
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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