STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG15186Uncharacterized protein, isoform F. (1120 aa)    
Predicted Functional Partners:
CG9815
Uncharacterized protein, isoform B.
      
 0.914
CG43901
Uncharacterized protein, isoform A; It is involved in the biological process described with: actin cytoskeleton organization.
      
 0.910
CG2016
Uncharacterized protein, isoform E.
   
  
 0.890
CD98hc
CD98 heavy chain (CD98hc) encodes a transporter involved in the transmembrane import of L-leucine.
      
 0.797
cwo
Transcription factor cwo; Plays a role in the regulation of circadian rhythms. Transcriptional repressor which inhibits Clock-mediated transcriptional activation by binding to E boxes in the promoters of Clock target genes and repressing their transcription. E box binding activity is time- dependent with higher binding activity seen in the early morning (zeitgeber time 2) than early evening (zeitgeber time 14) and is dependent on the presence of the circadian protein per. It is likely that per binds to Clock-cycle heterodimers, reducing their affinity for E box binding and allowing cwo [...]
      
 0.493
Rab18
GH11193p; Protein binding; GTPase activity; GTP binding. It is involved in the biological process described with: vesicle-mediated transport; Rab protein signal transduction; intracellular protein transport; lipid droplet organization.
      
 0.491
sing
Singles bar (sing) encodes a small multipass transmembrane protein that is required for muscle fusion in embryonic and adult stages. It is needed for progression beyond the pre-fusion complex stage of myoblast fusion, possibly by delivering fusion machinery components by vesicle fusion.
      
 0.430
TpnC73F
Troponin C, isoform 3; Enzyme regulator activity; calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization.
   
  
 0.428
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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