STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tkoTechnical knockout (tko) encodes the mitochondrial ribosomal protein S12. It is involved in the response to hypoxia and mechanosensory and courtship behaviors. (154 aa)    
Predicted Functional Partners:
bonsai
Bonsai (bonsai) encodes a mitochondrial small ribosomal protein that belongs to the universal S15 ribosomal protein US15m family. It is involved in growth regulation.
  
 0.999
mRpL36
Ribosomal protein; Structural constituent of ribosome. It is involved in the biological process described with: ribosome biogenesis; mitochondrial translation; Belongs to the bacterial ribosomal protein bL36 family.
  
 
 0.999
mRpS2
Mitochondrial ribosomal protein S2; Structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation.
  
 0.999
mRpS9
Mitochondrial ribosomal protein S9; RNA binding; structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation.
  
 0.999
mRpS10
28S ribosomal protein S10, mitochondrial; Structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation.
  
 0.999
mRpS16
Probable 28S ribosomal protein S16, mitochondrial; Structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation; Belongs to the bacterial ribosomal protein bS16 family.
  
 0.999
mRpS11
Mitochondrial ribosomal protein S11; mRNA 5'-UTR binding; structural constituent of ribosome; small ribosomal subunit rRNA binding. It is involved in the biological process described with: ribosomal small subunit assembly; translation; mitochondrial translation; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA).
  
 0.999
mRpS5
Mitochondrial ribosomal protein S5, isoform A; RNA binding; structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation; Belongs to the universal ribosomal protein uS5 family.
  
 0.999
mRpS6
Probable 28S ribosomal protein S6, mitochondrial; Structural constituent of ribosome; small ribosomal subunit rRNA binding. It is involved in the biological process described with: mitochondrial translation; translation; Belongs to the bacterial ribosomal protein bS6 family.
  
 0.999
mRpL17
Mitochondrial ribosomal protein L17, isoform A; Structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation.
  
 
 0.999
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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