STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gr22dGustatory receptor 22d (Gr22d) encodes a transmembrane domain protein unrelated to GPCRs that is predicted to mediate response to non-volatile compounds. (387 aa)    
Predicted Functional Partners:
CG33964
GM20958p.
      
 0.835
GstD5
Glutathione S-transferase D5; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May be involved in detoxification. Belongs to the GST superfamily. Delta family.
      
 0.790
Gr93b
Putative gustatory receptor 93b; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
   
  
 0.685
Gr39b
Putative gustatory receptor 39b; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates (By similarity). Has also atypical sensory function in organ not limited to conventional taste sensing like abdominal ganglions.
   
  
 0.674
MstProx
MstProx (MstProx) encodes a protein with an intracellular Toll/interleukin-1 receptor domain and extracellular Leucine-rich repeats. Although also designated as "Toll-3" and related to Tl, it is not known to activate the canonical Toll signaling pathway or antimicrobial response.
      
 0.670
Gr47a
Gustatory receptor; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family.
   
  
 0.627
Gr93c
Putative gustatory receptor 93c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
   
  
 0.624
Gr59c
Putative gustatory receptor 59c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
   
  
 0.622
Gr57a
Putative gustatory receptor 57a; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
   
  
 0.620
Gr58c
Putative gustatory receptor 58c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr10a subfamily.
   
  
 0.619
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.