STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slvSugar transporter SWEET1; Mediates both low-affinity uptake and efflux of sugar across the membrane. (226 aa)    
Predicted Functional Partners:
Hem
HEM-protein (Hem) encodes a component of the WAVE Regulatory Complex. Hem product regulates processes such as neuronal migration and asymmetric division of neural precursors by inhibiting the product of SCAR degradation. In the asymmetric process, the Hem-pathway indirectly maintains proper localization of proteins such as those encoded by insc and numb; Belongs to the HEM-1/HEM-2 family.
      
 0.660
Chs2
Chitin synthase activity. It is involved in the biological process described with: cuticle chitin biosynthetic process.
      
 0.531
kkv
Krotzkopf verkehrt (kkv) encodes a membrane-inserted glycosyltransferase family 2 chitin synthase that uses GlcNAc to produce the polysaccharide chitin, which is extruded to the differentiating cuticle and tracheal system (tracheal cuticle, tube diameter regulation and gas filling).
      
 0.463
eIF3e
Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In addition to its role in the eIF-3 complex, also functions in protein ubiquitination and degradation. During mitosis required for regulating mitotic mic [...]
      
 0.440
Cht12
Chitinase 12 (Cht12) encodes an enzyme involved in cuticle development, ecdysis and wound healing; Belongs to the glycosyl hydrolase 18 family.
      
 0.426
Cht11
Chitinase activity; chitin binding. It is involved in the biological process described with: chitin catabolic process; carbohydrate metabolic process; Belongs to the glycosyl hydrolase 18 family.
      
 0.424
Cht8
Chitinase 8; Chitin binding; chitinase activity. It is involved in the biological process described with: carbohydrate metabolic process; ecdysis, chitin-based cuticle; chitin catabolic process; Belongs to the glycosyl hydrolase 18 family.
      
 0.422
Cht9
Chitinase 9 (Cht9) encodes an enzyme involved in the formation of chitin-based extracellular matrix at barrier tissues; Belongs to the glycosyl hydrolase 18 family.
      
 0.422
Cht4
Chitinase 4 (Cht4) encodes a chitin binding protein with chitinolytic activity; Belongs to the glycosyl hydrolase 18 family.
      
 0.420
Cht7
Chitinase 7 (Cht7) encodes an enzyme involved in cuticle development, ecdysis and wound healing; Belongs to the glycosyl hydrolase 18 family.
      
 0.400
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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