STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ada2aTranscriptional adapter 2A; GCN5-independent Rpb4 complexes are highly enriched in decondensed chromosome puffs so may play a role in RNA polymerase II- dependent transcription. (562 aa)    
Predicted Functional Partners:
Gcn5
Gcn5 acetyltransferase (Gcn5) encodes a lysine acetyltransferase subunit of several chromatin modifying complexes. It contributes to oogenesis and metamorphosis.
    
 0.999
Ada3
Transcriptional Adaptor 3 (Ada3) encodes subunit of some chromatin modifying complexes.
   
 0.999
Sgf29
SAGA-associated factor 29kDa (Sgf29) encodes a encodes subunit of some chromatin modifying complexes.
   
 0.998
Atac1
Ada2a-containing complex component 1 (Atac1) encodes a protein involved in chromatin remodeling and histone acetylation.
  
 0.996
Spt3
FI01013p; Spt3 (Spt3) encodes a encodes a subunit of the SAGA chromatin modifying complex.
    
 0.995
Atac2
Ada2a-containing complex component 2 (Atac2) encodes a protein involved in chromatin organization, intestinal stem cell homeostasis, and histone acetylation.
   
 0.993
e(y)1
Transcription initiation factor TFIID subunit 9; Enhancer of yellow 1 (e(y)1) encodes a TAF9 protein and a main component of the Transcription factor II D (TFIID) complex. TFIID is involved in recruiting the transcription machinery to core promoters and organizing specific enhancer-promoter interactions.
    
 0.992
D12
D12 (D12) encodes a protein involved in chromatin remodeling and histone acetylation.
   
 0.990
Hcf
HCF C-terminal chain; May be involved in control of the cell cycle.
    
 0.990
Atac3
Ada2a-containing complex component 3 (Atac3) encodes a protein involved in chromatin remodeling and histone acetylation.
   
 0.989
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.