node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CycG | Rbcn-3B | FBpp0305520 | FBpp0310568 | Cyclin G; Cyclin with roles in multiple processes including transcription, meiotic recombination repair, cell cycle regulation, and promotion of normal growth and metabolism. Binds to the promoter region of the homeobox gene Abd-B and is involved in maintaining Abd-B expression in the pupal epithelium. Involved in the transcriptional repression of the homeotic genes Scr and Ubx. Plays a role in meiotic recombination repair of DNA double-strand breaks which ensures efficient translation of grk and promotes grk activity in the oocyte, leading to oocyte dorso-ventral axis formation follow [...] | Rabconnectin-3B, isoform A; Rabconnectin-3B (Rbcn-3B) encodes a protein that is part of a regulatory subunit of the Vacuolar H[+] ATPase required for acidification of intracellular vesicles and the lysosome. It involved in endocytic trafficking and lysosome function, and mutations block Notch signaling in follicle cells and imaginal disc cells. | 0.524 |
CycG | onecut | FBpp0305520 | FBpp0088173 | Cyclin G; Cyclin with roles in multiple processes including transcription, meiotic recombination repair, cell cycle regulation, and promotion of normal growth and metabolism. Binds to the promoter region of the homeobox gene Abd-B and is involved in maintaining Abd-B expression in the pupal epithelium. Involved in the transcriptional repression of the homeotic genes Scr and Ubx. Plays a role in meiotic recombination repair of DNA double-strand breaks which ensures efficient translation of grk and promotes grk activity in the oocyte, leading to oocyte dorso-ventral axis formation follow [...] | Homeobox protein onecut; Onecut (onecut) encodes a transcription factor that binds two different DNA motifs (Cut and Hox). It is mainly expressed in mature neurons and maintains neuronal identity. | 0.667 |
CycG | rdgC | FBpp0305520 | FBpp0309721 | Cyclin G; Cyclin with roles in multiple processes including transcription, meiotic recombination repair, cell cycle regulation, and promotion of normal growth and metabolism. Binds to the promoter region of the homeobox gene Abd-B and is involved in maintaining Abd-B expression in the pupal epithelium. Involved in the transcriptional repression of the homeotic genes Scr and Ubx. Plays a role in meiotic recombination repair of DNA double-strand breaks which ensures efficient translation of grk and promotes grk activity in the oocyte, leading to oocyte dorso-ventral axis formation follow [...] | Retinal degeneration C (rdgC) encodes a serine/threonine phosphatase that binds Ca2+/calmodulin and contains 2 Ca2+-binding EF-hand motifs. It promotes the dephosphorylation of the product of ninaE, which prevents its internalization. It also promotes the dephosphorylation of the product of trp at specific site affecting the frequency response to modulated light. | 0.561 |
Optix | Vsx1 | FBpp0302920 | FBpp0309431 | Optix (Optix) encodes a homeobox containing DNA binding protein and a member of the SIX class of proteins. It functions as a repressor via interaction with the transcriptional co-repressor encoded by gro. It is involved in eye formation and morphogenetic furrow movement. | Visual system homeobox 1 (Vsx1) encodes a transcription factor involved in the development of the visual-system. | 0.892 |
Optix | Vsx2 | FBpp0302920 | FBpp0309767 | Optix (Optix) encodes a homeobox containing DNA binding protein and a member of the SIX class of proteins. It functions as a repressor via interaction with the transcriptional co-repressor encoded by gro. It is involved in eye formation and morphogenetic furrow movement. | Visual system homeobox 2 (Vsx2) encodes a transcription factor involved in the development of the visual-system. | 0.860 |
Optix | acj6 | FBpp0302920 | FBpp0073832 | Optix (Optix) encodes a homeobox containing DNA binding protein and a member of the SIX class of proteins. It functions as a repressor via interaction with the transcriptional co-repressor encoded by gro. It is involved in eye formation and morphogenetic furrow movement. | Inhibitory POU protein; Modulates gene transcription; simultaneously generates both a specific activator and an inhibitor of gene transcription, capable of modulating two distinct regulatory programs during neural development. Has a role in olfactory behavior; Belongs to the POU transcription factor family. Class-4 subfamily. | 0.470 |
Optix | onecut | FBpp0302920 | FBpp0088173 | Optix (Optix) encodes a homeobox containing DNA binding protein and a member of the SIX class of proteins. It functions as a repressor via interaction with the transcriptional co-repressor encoded by gro. It is involved in eye formation and morphogenetic furrow movement. | Homeobox protein onecut; Onecut (onecut) encodes a transcription factor that binds two different DNA motifs (Cut and Hox). It is mainly expressed in mature neurons and maintains neuronal identity. | 0.630 |
Orc3 | onecut | FBpp0086881 | FBpp0088173 | Origin recognition complex subunit 3 (Orc3) encodes a subunit of the origin recognition complex. It is involved in DNA replication initiation and border follicle cell migration regulation. | Homeobox protein onecut; Onecut (onecut) encodes a transcription factor that binds two different DNA motifs (Cut and Hox). It is mainly expressed in mature neurons and maintains neuronal identity. | 0.745 |
Rbcn-3B | CycG | FBpp0310568 | FBpp0305520 | Rabconnectin-3B, isoform A; Rabconnectin-3B (Rbcn-3B) encodes a protein that is part of a regulatory subunit of the Vacuolar H[+] ATPase required for acidification of intracellular vesicles and the lysosome. It involved in endocytic trafficking and lysosome function, and mutations block Notch signaling in follicle cells and imaginal disc cells. | Cyclin G; Cyclin with roles in multiple processes including transcription, meiotic recombination repair, cell cycle regulation, and promotion of normal growth and metabolism. Binds to the promoter region of the homeobox gene Abd-B and is involved in maintaining Abd-B expression in the pupal epithelium. Involved in the transcriptional repression of the homeotic genes Scr and Ubx. Plays a role in meiotic recombination repair of DNA double-strand breaks which ensures efficient translation of grk and promotes grk activity in the oocyte, leading to oocyte dorso-ventral axis formation follow [...] | 0.524 |
Rbcn-3B | onecut | FBpp0310568 | FBpp0088173 | Rabconnectin-3B, isoform A; Rabconnectin-3B (Rbcn-3B) encodes a protein that is part of a regulatory subunit of the Vacuolar H[+] ATPase required for acidification of intracellular vesicles and the lysosome. It involved in endocytic trafficking and lysosome function, and mutations block Notch signaling in follicle cells and imaginal disc cells. | Homeobox protein onecut; Onecut (onecut) encodes a transcription factor that binds two different DNA motifs (Cut and Hox). It is mainly expressed in mature neurons and maintains neuronal identity. | 0.636 |
Rbcn-3B | rdgC | FBpp0310568 | FBpp0309721 | Rabconnectin-3B, isoform A; Rabconnectin-3B (Rbcn-3B) encodes a protein that is part of a regulatory subunit of the Vacuolar H[+] ATPase required for acidification of intracellular vesicles and the lysosome. It involved in endocytic trafficking and lysosome function, and mutations block Notch signaling in follicle cells and imaginal disc cells. | Retinal degeneration C (rdgC) encodes a serine/threonine phosphatase that binds Ca2+/calmodulin and contains 2 Ca2+-binding EF-hand motifs. It promotes the dephosphorylation of the product of ninaE, which prevents its internalization. It also promotes the dephosphorylation of the product of trp at specific site affecting the frequency response to modulated light. | 0.594 |
Vsx1 | Optix | FBpp0309431 | FBpp0302920 | Visual system homeobox 1 (Vsx1) encodes a transcription factor involved in the development of the visual-system. | Optix (Optix) encodes a homeobox containing DNA binding protein and a member of the SIX class of proteins. It functions as a repressor via interaction with the transcriptional co-repressor encoded by gro. It is involved in eye formation and morphogenetic furrow movement. | 0.892 |
Vsx1 | Vsx2 | FBpp0309431 | FBpp0309767 | Visual system homeobox 1 (Vsx1) encodes a transcription factor involved in the development of the visual-system. | Visual system homeobox 2 (Vsx2) encodes a transcription factor involved in the development of the visual-system. | 0.471 |
Vsx1 | acj6 | FBpp0309431 | FBpp0073832 | Visual system homeobox 1 (Vsx1) encodes a transcription factor involved in the development of the visual-system. | Inhibitory POU protein; Modulates gene transcription; simultaneously generates both a specific activator and an inhibitor of gene transcription, capable of modulating two distinct regulatory programs during neural development. Has a role in olfactory behavior; Belongs to the POU transcription factor family. Class-4 subfamily. | 0.664 |
Vsx1 | onecut | FBpp0309431 | FBpp0088173 | Visual system homeobox 1 (Vsx1) encodes a transcription factor involved in the development of the visual-system. | Homeobox protein onecut; Onecut (onecut) encodes a transcription factor that binds two different DNA motifs (Cut and Hox). It is mainly expressed in mature neurons and maintains neuronal identity. | 0.600 |
Vsx2 | Optix | FBpp0309767 | FBpp0302920 | Visual system homeobox 2 (Vsx2) encodes a transcription factor involved in the development of the visual-system. | Optix (Optix) encodes a homeobox containing DNA binding protein and a member of the SIX class of proteins. It functions as a repressor via interaction with the transcriptional co-repressor encoded by gro. It is involved in eye formation and morphogenetic furrow movement. | 0.860 |
Vsx2 | Vsx1 | FBpp0309767 | FBpp0309431 | Visual system homeobox 2 (Vsx2) encodes a transcription factor involved in the development of the visual-system. | Visual system homeobox 1 (Vsx1) encodes a transcription factor involved in the development of the visual-system. | 0.471 |
Vsx2 | acj6 | FBpp0309767 | FBpp0073832 | Visual system homeobox 2 (Vsx2) encodes a transcription factor involved in the development of the visual-system. | Inhibitory POU protein; Modulates gene transcription; simultaneously generates both a specific activator and an inhibitor of gene transcription, capable of modulating two distinct regulatory programs during neural development. Has a role in olfactory behavior; Belongs to the POU transcription factor family. Class-4 subfamily. | 0.657 |
Vsx2 | onecut | FBpp0309767 | FBpp0088173 | Visual system homeobox 2 (Vsx2) encodes a transcription factor involved in the development of the visual-system. | Homeobox protein onecut; Onecut (onecut) encodes a transcription factor that binds two different DNA motifs (Cut and Hox). It is mainly expressed in mature neurons and maintains neuronal identity. | 0.591 |
acj6 | Optix | FBpp0073832 | FBpp0302920 | Inhibitory POU protein; Modulates gene transcription; simultaneously generates both a specific activator and an inhibitor of gene transcription, capable of modulating two distinct regulatory programs during neural development. Has a role in olfactory behavior; Belongs to the POU transcription factor family. Class-4 subfamily. | Optix (Optix) encodes a homeobox containing DNA binding protein and a member of the SIX class of proteins. It functions as a repressor via interaction with the transcriptional co-repressor encoded by gro. It is involved in eye formation and morphogenetic furrow movement. | 0.470 |