node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG15445 | Drsl6 | FBpp0302762 | FBpp0072942 | LD38858p; It is involved in the biological process described with: regulation of ubiquitin-dependent protein catabolic process. | Drosomycin-like 6 (Drsl6) encodes a secreted peptide with homology to the antifungal peptide encoded by Drs. | 0.493 |
CG15445 | Nedd8 | FBpp0302762 | FBpp0309711 | LD38858p; It is involved in the biological process described with: regulation of ubiquitin-dependent protein catabolic process. | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control, embryogenesis and neurogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex Uba3-Ula1 and linkage to the E2 enzyme UbcE2M. Attachment of Nedd8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. | 0.850 |
CG15445 | Rad23 | FBpp0302762 | FBpp0305835 | LD38858p; It is involved in the biological process described with: regulation of ubiquitin-dependent protein catabolic process. | DNA repair protein Rad23; Rad23 (Rad23) encodes an evolutionarily conserved member of the proteasome-associated proteins. It acts as a shuttle -or bridge- protein helping ubiquitinated proteins to interact with the proteasome, which in turn regulates their turnover. | 0.481 |
CG15445 | Rpn10 | FBpp0302762 | FBpp0078024 | LD38858p; It is involved in the biological process described with: regulation of ubiquitin-dependent protein catabolic process. | Regulatory particle non-ATPase 10 (Rpn10) encodes one of the polyubiquitin receptor subunits of the 26S proteasome. It recognizes and binds the polyubiquitin moiety of proteins intended for proteasomal degradation or the ubiquitin-like domain of extraproteasomal ubiquitin receptors. | 0.822 |
CG15445 | Rpn13 | FBpp0302762 | FBpp0112986 | LD38858p; It is involved in the biological process described with: regulation of ubiquitin-dependent protein catabolic process. | Proteasomal ubiquitin receptor ADRM1 homolog; May function as a proteasomal ubiquitin receptor. May promote the deubiquitinating activity associated with the 26S proteasome (By similarity). | 0.493 |
CG15445 | achi | FBpp0302762 | FBpp0087053 | LD38858p; It is involved in the biological process described with: regulation of ubiquitin-dependent protein catabolic process. | Achintya, isoform C; Achintya (achi) encodes a homeodomain transcription factor (TGIF subclass) that is required along with homeodomain protein encoded by vis for meiotic division in spermatogenesis. | 0.753 |
CG15445 | nub | FBpp0302762 | FBpp0111554 | LD38858p; It is involved in the biological process described with: regulation of ubiquitin-dependent protein catabolic process. | Protein nubbin; DNA-binding regulatory protein implicated in early development. Involved in neuronal cell fate decision. Repressed directly or indirectly by the BX-C homeotic proteins. Belongs to the POU transcription factor family. Class-2 subfamily. | 0.546 |
CG15445 | pdm2 | FBpp0302762 | FBpp0309439 | LD38858p; It is involved in the biological process described with: regulation of ubiquitin-dependent protein catabolic process. | POU domain protein 2, isoform B; DNA-binding regulatory protein implicated in early development. Involved in neuronal cell fate decision. May act as an octamer-dependent activator of transcription. Could also play an early role in specific ectodermal cells, and a subsequent role in the embryonic nervous system. | 0.465 |
CG15445 | ubl | FBpp0302762 | FBpp0085529 | LD38858p; It is involved in the biological process described with: regulation of ubiquitin-dependent protein catabolic process. | Ubiquitin-like protein 5; Protein tag. It is involved in the biological process described with: mRNA splicing, via spliceosome; cellular protein modification process. | 0.450 |
CG15445 | vis | FBpp0302762 | FBpp0087056 | LD38858p; It is involved in the biological process described with: regulation of ubiquitin-dependent protein catabolic process. | Vismay, isoform B; Vismay (vis) encodes a transcription factor that contributes to spermatogenesis. | 0.753 |
Drsl6 | CG15445 | FBpp0072942 | FBpp0302762 | Drosomycin-like 6 (Drsl6) encodes a secreted peptide with homology to the antifungal peptide encoded by Drs. | LD38858p; It is involved in the biological process described with: regulation of ubiquitin-dependent protein catabolic process. | 0.493 |
Nedd8 | CG15445 | FBpp0309711 | FBpp0302762 | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control, embryogenesis and neurogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex Uba3-Ula1 and linkage to the E2 enzyme UbcE2M. Attachment of Nedd8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. | LD38858p; It is involved in the biological process described with: regulation of ubiquitin-dependent protein catabolic process. | 0.850 |
Nedd8 | Rad23 | FBpp0309711 | FBpp0305835 | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control, embryogenesis and neurogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex Uba3-Ula1 and linkage to the E2 enzyme UbcE2M. Attachment of Nedd8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. | DNA repair protein Rad23; Rad23 (Rad23) encodes an evolutionarily conserved member of the proteasome-associated proteins. It acts as a shuttle -or bridge- protein helping ubiquitinated proteins to interact with the proteasome, which in turn regulates their turnover. | 0.708 |
Nedd8 | Rpn10 | FBpp0309711 | FBpp0078024 | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control, embryogenesis and neurogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex Uba3-Ula1 and linkage to the E2 enzyme UbcE2M. Attachment of Nedd8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. | Regulatory particle non-ATPase 10 (Rpn10) encodes one of the polyubiquitin receptor subunits of the 26S proteasome. It recognizes and binds the polyubiquitin moiety of proteins intended for proteasomal degradation or the ubiquitin-like domain of extraproteasomal ubiquitin receptors. | 0.907 |
Nedd8 | Rpn13 | FBpp0309711 | FBpp0112986 | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control, embryogenesis and neurogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex Uba3-Ula1 and linkage to the E2 enzyme UbcE2M. Attachment of Nedd8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. | Proteasomal ubiquitin receptor ADRM1 homolog; May function as a proteasomal ubiquitin receptor. May promote the deubiquitinating activity associated with the 26S proteasome (By similarity). | 0.604 |
Nedd8 | ubl | FBpp0309711 | FBpp0085529 | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control, embryogenesis and neurogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex Uba3-Ula1 and linkage to the E2 enzyme UbcE2M. Attachment of Nedd8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. | Ubiquitin-like protein 5; Protein tag. It is involved in the biological process described with: mRNA splicing, via spliceosome; cellular protein modification process. | 0.979 |
Rad23 | CG15445 | FBpp0305835 | FBpp0302762 | DNA repair protein Rad23; Rad23 (Rad23) encodes an evolutionarily conserved member of the proteasome-associated proteins. It acts as a shuttle -or bridge- protein helping ubiquitinated proteins to interact with the proteasome, which in turn regulates their turnover. | LD38858p; It is involved in the biological process described with: regulation of ubiquitin-dependent protein catabolic process. | 0.481 |
Rad23 | Nedd8 | FBpp0305835 | FBpp0309711 | DNA repair protein Rad23; Rad23 (Rad23) encodes an evolutionarily conserved member of the proteasome-associated proteins. It acts as a shuttle -or bridge- protein helping ubiquitinated proteins to interact with the proteasome, which in turn regulates their turnover. | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control, embryogenesis and neurogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex Uba3-Ula1 and linkage to the E2 enzyme UbcE2M. Attachment of Nedd8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. | 0.708 |
Rad23 | Rpn10 | FBpp0305835 | FBpp0078024 | DNA repair protein Rad23; Rad23 (Rad23) encodes an evolutionarily conserved member of the proteasome-associated proteins. It acts as a shuttle -or bridge- protein helping ubiquitinated proteins to interact with the proteasome, which in turn regulates their turnover. | Regulatory particle non-ATPase 10 (Rpn10) encodes one of the polyubiquitin receptor subunits of the 26S proteasome. It recognizes and binds the polyubiquitin moiety of proteins intended for proteasomal degradation or the ubiquitin-like domain of extraproteasomal ubiquitin receptors. | 0.996 |
Rad23 | Rpn13 | FBpp0305835 | FBpp0112986 | DNA repair protein Rad23; Rad23 (Rad23) encodes an evolutionarily conserved member of the proteasome-associated proteins. It acts as a shuttle -or bridge- protein helping ubiquitinated proteins to interact with the proteasome, which in turn regulates their turnover. | Proteasomal ubiquitin receptor ADRM1 homolog; May function as a proteasomal ubiquitin receptor. May promote the deubiquitinating activity associated with the 26S proteasome (By similarity). | 0.962 |