STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG7906Uncharacterized protein, isoform B. (356 aa)    
Predicted Functional Partners:
CG7924
LP03067p.
   
    0.999
e
LP19442p; Ebony (e) encodes a protein that links beta-alanine to biogenic amines like dopamine or histamine. It controls the amount of free biogenic amine, e.g. of dopamine in cuticle formation and of histamine in visual signal transduction of the eye. It is also involved in behavioral rhythmicity.
   
    0.839
w
White (w) encodes a member of the ABCG2 class of transporters, transporting molecules such as cyclic GMP, biogenic amines and pigments including drosopterins and ommochromes. Mutation of w results in viable flies with white eyes. A shortened version of the gene (mini-w) has been widely used in transformation constructs as a selectable marker.
      
 0.836
Eig71Ec
Ecdysone-induced gene 71Ec; It is involved in the biological process described with: defense response to bacterium; metamorphosis.
   
    0.750
Drsl3
Drosomycin-like 3 (Drsl3) encodes a secreted peptide with homology to the antifungal peptide encoded by Drs. It is expressed in the gut under the control of the JAK-STAT pathway.
      
 0.676
Jon65Aiv
Jonah 65Aiv; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
      
 0.672
CG4151
LP05252p.
   
    0.657
ple
Pale (ple) encodes a tyrosine hydroxylase, the first and rate-limiting step in the synthesis of dopamine (and eventually, melanin). Dopamine has critical roles in system development.
   
    0.623
santa-maria
Scavenger receptor acting in neural tissue and majority of rhodopsin is absent (santa-maria) encodes a class B scavenger receptor that contributes to the conversion of carotenoids to vitamin A. It is involved in phototransduction and thermotaxis; Belongs to the CD36 family.
   
    0.583
CG7778
GH17475p.
   
    0.577
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.