node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG9175 | Grasp65 | FBpp0078842 | FBpp0074664 | FI09914p; GTPase activator activity; Sar guanyl-nucleotide exchange factor activity; GTPase binding. It is involved in the biological process described with: cell morphogenesis; regulation of COPII vesicle coating; protein secretion. | Grasp65 (Grasp65) encodes a myristoylated Golgi protein that binds the product of GM130 and has been shown to mediate the Golgi bypass of transmembrane proteins. | 0.586 |
CG9175 | Sar1 | FBpp0078842 | FBpp0083607 | FI09914p; GTPase activator activity; Sar guanyl-nucleotide exchange factor activity; GTPase binding. It is involved in the biological process described with: cell morphogenesis; regulation of COPII vesicle coating; protein secretion. | Secretion-associated Ras-related 1 (Sar1) encodes a small GTPase that is recruited to the endoplasmic reticulum and initiates the recruitment of the COPII subunit complex Sec23/Sec24. | 0.999 |
CG9175 | Sec13 | FBpp0078842 | FBpp0311988 | FI09914p; GTPase activator activity; Sar guanyl-nucleotide exchange factor activity; GTPase binding. It is involved in the biological process described with: cell morphogenesis; regulation of COPII vesicle coating; protein secretion. | Protein SEC13 homolog; Functions as a component of the nuclear pore complex (NPC) and the COPII coat (By similarity). At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles (By similarity). Recruited to transcriptionally active chromatin at the time of transcription initiation by RNA polymerase II. Required for proper expression of ecdysone-responsive genes such as Eip74EF and Eip75B during larval development. Required for reactivation of transcription after heat shock. Required for nuclear import of phosphorylated Mad via importin msk. Has no role i [...] | 0.982 |
CG9175 | Sec16 | FBpp0078842 | FBpp0309104 | FI09914p; GTPase activator activity; Sar guanyl-nucleotide exchange factor activity; GTPase binding. It is involved in the biological process described with: cell morphogenesis; regulation of COPII vesicle coating; protein secretion. | Secretory 16 (Sec16) encodes a protein involved in the organization of endoplasmic reticulum exit sites. It contributes to stress response to amino-acid starvation, during which it mediates the formation of both Sec bodies and stress granules. | 0.973 |
CG9175 | Sec23 | FBpp0078842 | FBpp0301099 | FI09914p; GTPase activator activity; Sar guanyl-nucleotide exchange factor activity; GTPase binding. It is involved in the biological process described with: cell morphogenesis; regulation of COPII vesicle coating; protein secretion. | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.991 |
CG9175 | Sec24AB | FBpp0078842 | FBpp0308496 | FI09914p; GTPase activator activity; Sar guanyl-nucleotide exchange factor activity; GTPase binding. It is involved in the biological process described with: cell morphogenesis; regulation of COPII vesicle coating; protein secretion. | Secretory 24AB, isoform A; Zinc ion binding; signal sequence binding. It is involved in the biological process described with: COPII-coated vesicle cargo loading; intracellular protein transport. | 0.931 |
CG9175 | Sec24CD | FBpp0078842 | FBpp0303000 | FI09914p; GTPase activator activity; Sar guanyl-nucleotide exchange factor activity; GTPase binding. It is involved in the biological process described with: cell morphogenesis; regulation of COPII vesicle coating; protein secretion. | Secretory 24CD (Sec24CD) encodes a subunit of the coat protein complex of COPII vesicles, which transport cargo from the endoplasmic reticulum to the Golgi apparatus. It is essential for export of membrane and secreted proteins from the endoplasmic reticulum. It is involved in epithelial morphogenesis and differentiation. | 0.898 |
CG9175 | Sec31 | FBpp0078842 | FBpp0311417 | FI09914p; GTPase activator activity; Sar guanyl-nucleotide exchange factor activity; GTPase binding. It is involved in the biological process described with: cell morphogenesis; regulation of COPII vesicle coating; protein secretion. | Secretory 31 (Sec31) encodes a protein involved in the innate immune response. | 0.971 |
CG9175 | Syx5 | FBpp0078842 | FBpp0080390 | FI09914p; GTPase activator activity; Sar guanyl-nucleotide exchange factor activity; GTPase binding. It is involved in the biological process described with: cell morphogenesis; regulation of COPII vesicle coating; protein secretion. | Syntaxin-5; Syntaxin 5 (Syx5) encodes a type II transmembrane protein in the Q-SNARE family that forms hetero tetramers required for membrane function in the early secretory pathway (ER and Golgi). It has been involved in cytokinesis during spermatogenesis. | 0.869 |
CG9175 | p115 | FBpp0078842 | FBpp0309148 | FI09914p; GTPase activator activity; Sar guanyl-nucleotide exchange factor activity; GTPase binding. It is involved in the biological process described with: cell morphogenesis; regulation of COPII vesicle coating; protein secretion. | General vesicular transport factor p115; Essential for maintaining the architecture of the Golgi stacks and for normal organization of the transitional endoplasmic reticulum (tER). Required for both the formation of the Golgi stacks and the maintenance of the individual cisternae. Belongs to the VDP/USO1/EDE1 family. | 0.627 |
Grasp65 | CG9175 | FBpp0074664 | FBpp0078842 | Grasp65 (Grasp65) encodes a myristoylated Golgi protein that binds the product of GM130 and has been shown to mediate the Golgi bypass of transmembrane proteins. | FI09914p; GTPase activator activity; Sar guanyl-nucleotide exchange factor activity; GTPase binding. It is involved in the biological process described with: cell morphogenesis; regulation of COPII vesicle coating; protein secretion. | 0.586 |
Grasp65 | Sar1 | FBpp0074664 | FBpp0083607 | Grasp65 (Grasp65) encodes a myristoylated Golgi protein that binds the product of GM130 and has been shown to mediate the Golgi bypass of transmembrane proteins. | Secretion-associated Ras-related 1 (Sar1) encodes a small GTPase that is recruited to the endoplasmic reticulum and initiates the recruitment of the COPII subunit complex Sec23/Sec24. | 0.504 |
Grasp65 | Sec13 | FBpp0074664 | FBpp0311988 | Grasp65 (Grasp65) encodes a myristoylated Golgi protein that binds the product of GM130 and has been shown to mediate the Golgi bypass of transmembrane proteins. | Protein SEC13 homolog; Functions as a component of the nuclear pore complex (NPC) and the COPII coat (By similarity). At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles (By similarity). Recruited to transcriptionally active chromatin at the time of transcription initiation by RNA polymerase II. Required for proper expression of ecdysone-responsive genes such as Eip74EF and Eip75B during larval development. Required for reactivation of transcription after heat shock. Required for nuclear import of phosphorylated Mad via importin msk. Has no role i [...] | 0.755 |
Grasp65 | Sec16 | FBpp0074664 | FBpp0309104 | Grasp65 (Grasp65) encodes a myristoylated Golgi protein that binds the product of GM130 and has been shown to mediate the Golgi bypass of transmembrane proteins. | Secretory 16 (Sec16) encodes a protein involved in the organization of endoplasmic reticulum exit sites. It contributes to stress response to amino-acid starvation, during which it mediates the formation of both Sec bodies and stress granules. | 0.682 |
Grasp65 | Sec23 | FBpp0074664 | FBpp0301099 | Grasp65 (Grasp65) encodes a myristoylated Golgi protein that binds the product of GM130 and has been shown to mediate the Golgi bypass of transmembrane proteins. | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.930 |
Grasp65 | Sec24AB | FBpp0074664 | FBpp0308496 | Grasp65 (Grasp65) encodes a myristoylated Golgi protein that binds the product of GM130 and has been shown to mediate the Golgi bypass of transmembrane proteins. | Secretory 24AB, isoform A; Zinc ion binding; signal sequence binding. It is involved in the biological process described with: COPII-coated vesicle cargo loading; intracellular protein transport. | 0.813 |
Grasp65 | Sec24CD | FBpp0074664 | FBpp0303000 | Grasp65 (Grasp65) encodes a myristoylated Golgi protein that binds the product of GM130 and has been shown to mediate the Golgi bypass of transmembrane proteins. | Secretory 24CD (Sec24CD) encodes a subunit of the coat protein complex of COPII vesicles, which transport cargo from the endoplasmic reticulum to the Golgi apparatus. It is essential for export of membrane and secreted proteins from the endoplasmic reticulum. It is involved in epithelial morphogenesis and differentiation. | 0.871 |
Grasp65 | Sec31 | FBpp0074664 | FBpp0311417 | Grasp65 (Grasp65) encodes a myristoylated Golgi protein that binds the product of GM130 and has been shown to mediate the Golgi bypass of transmembrane proteins. | Secretory 31 (Sec31) encodes a protein involved in the innate immune response. | 0.612 |
Grasp65 | Syx5 | FBpp0074664 | FBpp0080390 | Grasp65 (Grasp65) encodes a myristoylated Golgi protein that binds the product of GM130 and has been shown to mediate the Golgi bypass of transmembrane proteins. | Syntaxin-5; Syntaxin 5 (Syx5) encodes a type II transmembrane protein in the Q-SNARE family that forms hetero tetramers required for membrane function in the early secretory pathway (ER and Golgi). It has been involved in cytokinesis during spermatogenesis. | 0.948 |
Grasp65 | p115 | FBpp0074664 | FBpp0309148 | Grasp65 (Grasp65) encodes a myristoylated Golgi protein that binds the product of GM130 and has been shown to mediate the Golgi bypass of transmembrane proteins. | General vesicular transport factor p115; Essential for maintaining the architecture of the Golgi stacks and for normal organization of the transitional endoplasmic reticulum (tER). Required for both the formation of the Golgi stacks and the maintenance of the individual cisternae. Belongs to the VDP/USO1/EDE1 family. | 0.976 |