STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
unc80Protein unc-80 homolog; Component of the na (narrow abdomen) sodium channel complex. In the circadian clock neurons it functions with na and unc79 to promote circadian rhythmicity; Belongs to the unc-80 family. (3332 aa)    
Predicted Functional Partners:
unc79
Uncoordinated 79 (unc79) encodes a protein involved in circadian locomotor rhythms.
   
 0.999
na
Narrow abdomen, isoform F; Narrow abdomen (na) encodes an ion channel involved in circadian locomotor rhythms and touch perception.
   
 0.999
Mid1
Mid1, isoform A; Stretch-activated, cation-selective, calcium channel activity. It is involved in the biological process described with: calcium ion import across plasma membrane; social behavior; locomotor rhythm.
   
 
 0.718
Nca
Neurocalcin homolog; Calcium-binding protein that is essential for promoting night-time sleep and inhibiting nocturnal hyperactivity. During the night-time it promotes sleep by limiting synaptic output from arousal- and wake-promoting neurons within the C01- and A05- domains that include the mushroom body, and the antennal mechanosensory and motor center. Regulated by the circadian clock network and light- sensing circuits that include the CRY photoreceptor; it is likely that both of these internal and external cues are required to define the temporal window (the night-time) during whi [...]
   
 
 0.641
CG2157
Uncharacterized protein, isoform B.
    
 
 0.626
CG4587
Uncharacterized protein, isoform H; Voltage-gated calcium channel activity.
   
  
 0.516
primo-1
Low molecular weight phosphotyrosine protein phosphatase 1; Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
    
 
 0.499
primo-2
Low molecular weight phosphotyrosine protein phosphatase 2; Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
    
 
 0.496
Task6
TWIK-related acid-sensitive K[+] channel 6 (Task6) encodes an ion channel involved in the transmembrane transport of potassium.
   
  
 0.484
CG1271
HL01494p; Glycerol kinase activity; phosphotransferase activity, alcohol group as acceptor. It is involved in the biological process described with: glycerol-3-phosphate biosynthetic process; triglyceride metabolic process; phosphorylation; glycerol metabolic process.
    
 
 0.478
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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