node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG5521 | CG9727 | FBpp0290357 | FBpp0303225 | Probable Rho GTPase-activating protein CG5521; GTPase activator activity. It is involved in the biological process described with: regulation of small GTPase mediated signal transduction; positive regulation of GTPase activity. | Uncharacterized protein, isoform B; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | 0.497 |
CG9727 | CG5521 | FBpp0303225 | FBpp0290357 | Uncharacterized protein, isoform B; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Probable Rho GTPase-activating protein CG5521; GTPase activator activity. It is involved in the biological process described with: regulation of small GTPase mediated signal transduction; positive regulation of GTPase activity. | 0.497 |
CG9727 | CycK | FBpp0303225 | FBpp0310472 | Uncharacterized protein, isoform B; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Cyclin K (CycK) encodes a Cyclin-homologous subunit that forms a complex with the transcriptional kinase encoded by Cdk12. This complex phosphorylates the carboxy terminal domain of the large subunit of RNA polymerase II (encoded by RpII215) and contributes to pre-mRNA processing, transcription and chromatin structure. | 0.426 |
CG9727 | Hel89B | FBpp0303225 | FBpp0290929 | Uncharacterized protein, isoform B; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Helicase 89B (Hel89B) encodes a protein that belongs to the SNF2 family of chromatin regulators. Hel89B product binds to large number of sites on polytene chromosomes and positively regulates the expression of antimicrobial peptide genes. | 0.426 |
CG9727 | IFT46 | FBpp0303225 | FBpp0080628 | Uncharacterized protein, isoform B; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Intraflagellar transport 46; It is involved in the biological process described with: intraciliary transport; cilium assembly. | 0.481 |
CG9727 | IFT52 | FBpp0303225 | FBpp0078962 | Uncharacterized protein, isoform B; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Intraflagellar transport 52. | 0.487 |
CG9727 | Nf1 | FBpp0303225 | FBpp0084326 | Uncharacterized protein, isoform B; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Neurofibromin 1 (Nf1) encodes a protein that functions as a GTPase activating protein for the products of Ras85D and Ras64B in the larval and adult nervous system. Loss of Nf1 results in excess Ras-Raf-ERK signaling and to a non-cell-autonomous cAMP/PKA signaling defect. The product of Nf1 contributes to postembryonic growth, learning/memory, and circadian rhythm. | 0.477 |
CG9727 | Oseg2 | FBpp0303225 | FBpp0304907 | Uncharacterized protein, isoform B; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia. Belongs to the IFT172 family. | 0.700 |
CG9727 | lok | FBpp0303225 | FBpp0080860 | Uncharacterized protein, isoform B; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Ovarian-specific serine/threonine-protein kinase Lok; May have a role in germline establishment. | 0.781 |
CG9727 | mei-41 | FBpp0303225 | FBpp0074047 | Uncharacterized protein, isoform B; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Serine/threonine-protein kinase ATR; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates various proteins, which collectively inhibits DNA replication and mitosis and promotes DNA repair and recombination. Phosphorylates grp/CHK1. Phosphorylates 'Ser-137' of histone variant H2AX/H2AV at sites of DNA damage, thereby regulating DNA damage response mechanism. [...] | 0.890 |
CG9727 | nompB | FBpp0303225 | FBpp0309502 | Uncharacterized protein, isoform B; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | No mechanoreceptor potential B (nompB) encodes an essential component of the conserved intraflagellar transport mechanism, which is needed to extend cilia above the cell surface. nompB mutants have truncated, nonfunctional sensory cilia with consequent mechanosensory deficits. | 0.512 |
CycK | CG9727 | FBpp0310472 | FBpp0303225 | Cyclin K (CycK) encodes a Cyclin-homologous subunit that forms a complex with the transcriptional kinase encoded by Cdk12. This complex phosphorylates the carboxy terminal domain of the large subunit of RNA polymerase II (encoded by RpII215) and contributes to pre-mRNA processing, transcription and chromatin structure. | Uncharacterized protein, isoform B; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | 0.426 |
Hel89B | CG9727 | FBpp0290929 | FBpp0303225 | Helicase 89B (Hel89B) encodes a protein that belongs to the SNF2 family of chromatin regulators. Hel89B product binds to large number of sites on polytene chromosomes and positively regulates the expression of antimicrobial peptide genes. | Uncharacterized protein, isoform B; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | 0.426 |
IFT46 | CG9727 | FBpp0080628 | FBpp0303225 | Intraflagellar transport 46; It is involved in the biological process described with: intraciliary transport; cilium assembly. | Uncharacterized protein, isoform B; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | 0.481 |
IFT46 | IFT52 | FBpp0080628 | FBpp0078962 | Intraflagellar transport 46; It is involved in the biological process described with: intraciliary transport; cilium assembly. | Intraflagellar transport 52. | 0.999 |
IFT46 | Oseg2 | FBpp0080628 | FBpp0304907 | Intraflagellar transport 46; It is involved in the biological process described with: intraciliary transport; cilium assembly. | Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia. Belongs to the IFT172 family. | 0.968 |
IFT46 | nompB | FBpp0080628 | FBpp0309502 | Intraflagellar transport 46; It is involved in the biological process described with: intraciliary transport; cilium assembly. | No mechanoreceptor potential B (nompB) encodes an essential component of the conserved intraflagellar transport mechanism, which is needed to extend cilia above the cell surface. nompB mutants have truncated, nonfunctional sensory cilia with consequent mechanosensory deficits. | 0.999 |
IFT52 | CG9727 | FBpp0078962 | FBpp0303225 | Intraflagellar transport 52. | Uncharacterized protein, isoform B; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | 0.487 |
IFT52 | IFT46 | FBpp0078962 | FBpp0080628 | Intraflagellar transport 52. | Intraflagellar transport 46; It is involved in the biological process described with: intraciliary transport; cilium assembly. | 0.999 |
IFT52 | Oseg2 | FBpp0078962 | FBpp0304907 | Intraflagellar transport 52. | Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia. Belongs to the IFT172 family. | 0.995 |