node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CASK | Cib2 | FBpp0303394 | FBpp0293260 | Peripheral plasma membrane protein CASK; CASK (CASK) encodes a member of the MAGUK family of scaffolding proteins. In epithelial tissues, the product of CASK functions as an adhesion molecule involved in cell proliferation, cytoskeletal remodeling and cell migration. In neurons, the product of CASK serves as a scaffold for a number of signaling and transmembrane molecules and is involved in synaptic development and plasticity. | Calcium and integrin binding family member 2; Calcium ion binding; calcium-dependent protein serine/threonine phosphatase activity. It is involved in the biological process described with: calcium ion homeostasis; phototransduction. | 0.676 |
CASK | dysc | FBpp0303394 | FBpp0303444 | Peripheral plasma membrane protein CASK; CASK (CASK) encodes a member of the MAGUK family of scaffolding proteins. In epithelial tissues, the product of CASK functions as an adhesion molecule involved in cell proliferation, cytoskeletal remodeling and cell migration. In neurons, the product of CASK serves as a scaffold for a number of signaling and transmembrane molecules and is involved in synaptic development and plasticity. | Dyschronic, isoform G; Dyschronic (dysc) encodes a protein that regulates the localization of the calcium-activated potassium channel encoded by slo. The product of dysc impacts circadian locomotor patterns, synaptic morphology, active zone structure, and both spontaneous and evoked neurotransmitter release. | 0.782 |
CASK | pins | FBpp0303394 | FBpp0084559 | Peripheral plasma membrane protein CASK; CASK (CASK) encodes a member of the MAGUK family of scaffolding proteins. In epithelial tissues, the product of CASK functions as an adhesion molecule involved in cell proliferation, cytoskeletal remodeling and cell migration. In neurons, the product of CASK serves as a scaffold for a number of signaling and transmembrane molecules and is involved in synaptic development and plasticity. | Partner of inscuteable (pins) encodes a GDP-dissociation inhibitor involved in asymmetric cell division and mitotic spindle orientation. | 0.554 |
CASK | slo | FBpp0303394 | FBpp0303318 | Peripheral plasma membrane protein CASK; CASK (CASK) encodes a member of the MAGUK family of scaffolding proteins. In epithelial tissues, the product of CASK functions as an adhesion molecule involved in cell proliferation, cytoskeletal remodeling and cell migration. In neurons, the product of CASK serves as a scaffold for a number of signaling and transmembrane molecules and is involved in synaptic development and plasticity. | Calcium-activated potassium channel slowpoke; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Kinetics are determined by alternative splicing, phosphorylation status and its combination interaction with Slob and 14-3-3-zeta. While the interaction with Slob1 alone increases its activity, its interaction with both Slob [...] | 0.420 |
CG5921 | Cad99C | FBpp0293886 | FBpp0084854 | Uncharacterized protein, isoform D; Actin filament binding; spectrin binding. It is involved in the biological process described with: sensory perception of sound; G2/M transition of mitotic cell cycle. | Cadherin-99C; Cadherin that functions in epithelial morphogenesis and the intestine epithelial immune response. Essential for female fertility. Regulates the length and organization of apical microvilli in developing follicle cells and salivary glands. Function in the follicle cell is essential for egg development as the microvilli secrete eggshell material such as the vitelline membrane. Acts at least in part by regulating the recruitment of the myosin ck to the follicle cell microvilli. Also required to regulate cell rearrangements during salivary tube elongation, possibly by modulat [...] | 0.967 |
CG5921 | Cib2 | FBpp0293886 | FBpp0293260 | Uncharacterized protein, isoform D; Actin filament binding; spectrin binding. It is involved in the biological process described with: sensory perception of sound; G2/M transition of mitotic cell cycle. | Calcium and integrin binding family member 2; Calcium ion binding; calcium-dependent protein serine/threonine phosphatase activity. It is involved in the biological process described with: calcium ion homeostasis; phototransduction. | 0.673 |
CG5921 | Myo28B1 | FBpp0293886 | FBpp0079097 | Uncharacterized protein, isoform D; Actin filament binding; spectrin binding. It is involved in the biological process described with: sensory perception of sound; G2/M transition of mitotic cell cycle. | Myosin 28B1 (Myo28B1) encodes a high duty ratio motor protein belonging to the MyTH4-FERM subgroup of actin-based molecular motors; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.986 |
CG5921 | ck | FBpp0293886 | FBpp0310275 | Uncharacterized protein, isoform D; Actin filament binding; spectrin binding. It is involved in the biological process described with: sensory perception of sound; G2/M transition of mitotic cell cycle. | Myosin-VIIa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements: can function in cells as a single-molecule cargo transporter. A very slow and high-duty-ratio motor, may be suitable for tension maintenance of actin filaments. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Plays a key role in the formation of cellular projections and other actin-based functions required for embryonic and larval viability. Necessary for auditory transduction: [...] | 0.986 |
CG5921 | dysc | FBpp0293886 | FBpp0303444 | Uncharacterized protein, isoform D; Actin filament binding; spectrin binding. It is involved in the biological process described with: sensory perception of sound; G2/M transition of mitotic cell cycle. | Dyschronic, isoform G; Dyschronic (dysc) encodes a protein that regulates the localization of the calcium-activated potassium channel encoded by slo. The product of dysc impacts circadian locomotor patterns, synaptic morphology, active zone structure, and both spontaneous and evoked neurotransmitter release. | 0.910 |
CG5921 | nompB | FBpp0293886 | FBpp0309502 | Uncharacterized protein, isoform D; Actin filament binding; spectrin binding. It is involved in the biological process described with: sensory perception of sound; G2/M transition of mitotic cell cycle. | No mechanoreceptor potential B (nompB) encodes an essential component of the conserved intraflagellar transport mechanism, which is needed to extend cilia above the cell surface. nompB mutants have truncated, nonfunctional sensory cilia with consequent mechanosensory deficits. | 0.455 |
Cad99C | CG5921 | FBpp0084854 | FBpp0293886 | Cadherin-99C; Cadherin that functions in epithelial morphogenesis and the intestine epithelial immune response. Essential for female fertility. Regulates the length and organization of apical microvilli in developing follicle cells and salivary glands. Function in the follicle cell is essential for egg development as the microvilli secrete eggshell material such as the vitelline membrane. Acts at least in part by regulating the recruitment of the myosin ck to the follicle cell microvilli. Also required to regulate cell rearrangements during salivary tube elongation, possibly by modulat [...] | Uncharacterized protein, isoform D; Actin filament binding; spectrin binding. It is involved in the biological process described with: sensory perception of sound; G2/M transition of mitotic cell cycle. | 0.967 |
Cad99C | Cib2 | FBpp0084854 | FBpp0293260 | Cadherin-99C; Cadherin that functions in epithelial morphogenesis and the intestine epithelial immune response. Essential for female fertility. Regulates the length and organization of apical microvilli in developing follicle cells and salivary glands. Function in the follicle cell is essential for egg development as the microvilli secrete eggshell material such as the vitelline membrane. Acts at least in part by regulating the recruitment of the myosin ck to the follicle cell microvilli. Also required to regulate cell rearrangements during salivary tube elongation, possibly by modulat [...] | Calcium and integrin binding family member 2; Calcium ion binding; calcium-dependent protein serine/threonine phosphatase activity. It is involved in the biological process described with: calcium ion homeostasis; phototransduction. | 0.605 |
Cad99C | Myo28B1 | FBpp0084854 | FBpp0079097 | Cadherin-99C; Cadherin that functions in epithelial morphogenesis and the intestine epithelial immune response. Essential for female fertility. Regulates the length and organization of apical microvilli in developing follicle cells and salivary glands. Function in the follicle cell is essential for egg development as the microvilli secrete eggshell material such as the vitelline membrane. Acts at least in part by regulating the recruitment of the myosin ck to the follicle cell microvilli. Also required to regulate cell rearrangements during salivary tube elongation, possibly by modulat [...] | Myosin 28B1 (Myo28B1) encodes a high duty ratio motor protein belonging to the MyTH4-FERM subgroup of actin-based molecular motors; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.941 |
Cad99C | ck | FBpp0084854 | FBpp0310275 | Cadherin-99C; Cadherin that functions in epithelial morphogenesis and the intestine epithelial immune response. Essential for female fertility. Regulates the length and organization of apical microvilli in developing follicle cells and salivary glands. Function in the follicle cell is essential for egg development as the microvilli secrete eggshell material such as the vitelline membrane. Acts at least in part by regulating the recruitment of the myosin ck to the follicle cell microvilli. Also required to regulate cell rearrangements during salivary tube elongation, possibly by modulat [...] | Myosin-VIIa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements: can function in cells as a single-molecule cargo transporter. A very slow and high-duty-ratio motor, may be suitable for tension maintenance of actin filaments. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Plays a key role in the formation of cellular projections and other actin-based functions required for embryonic and larval viability. Necessary for auditory transduction: [...] | 0.980 |
Cad99C | dysc | FBpp0084854 | FBpp0303444 | Cadherin-99C; Cadherin that functions in epithelial morphogenesis and the intestine epithelial immune response. Essential for female fertility. Regulates the length and organization of apical microvilli in developing follicle cells and salivary glands. Function in the follicle cell is essential for egg development as the microvilli secrete eggshell material such as the vitelline membrane. Acts at least in part by regulating the recruitment of the myosin ck to the follicle cell microvilli. Also required to regulate cell rearrangements during salivary tube elongation, possibly by modulat [...] | Dyschronic, isoform G; Dyschronic (dysc) encodes a protein that regulates the localization of the calcium-activated potassium channel encoded by slo. The product of dysc impacts circadian locomotor patterns, synaptic morphology, active zone structure, and both spontaneous and evoked neurotransmitter release. | 0.900 |
Cib2 | CASK | FBpp0293260 | FBpp0303394 | Calcium and integrin binding family member 2; Calcium ion binding; calcium-dependent protein serine/threonine phosphatase activity. It is involved in the biological process described with: calcium ion homeostasis; phototransduction. | Peripheral plasma membrane protein CASK; CASK (CASK) encodes a member of the MAGUK family of scaffolding proteins. In epithelial tissues, the product of CASK functions as an adhesion molecule involved in cell proliferation, cytoskeletal remodeling and cell migration. In neurons, the product of CASK serves as a scaffold for a number of signaling and transmembrane molecules and is involved in synaptic development and plasticity. | 0.676 |
Cib2 | CG5921 | FBpp0293260 | FBpp0293886 | Calcium and integrin binding family member 2; Calcium ion binding; calcium-dependent protein serine/threonine phosphatase activity. It is involved in the biological process described with: calcium ion homeostasis; phototransduction. | Uncharacterized protein, isoform D; Actin filament binding; spectrin binding. It is involved in the biological process described with: sensory perception of sound; G2/M transition of mitotic cell cycle. | 0.673 |
Cib2 | Cad99C | FBpp0293260 | FBpp0084854 | Calcium and integrin binding family member 2; Calcium ion binding; calcium-dependent protein serine/threonine phosphatase activity. It is involved in the biological process described with: calcium ion homeostasis; phototransduction. | Cadherin-99C; Cadherin that functions in epithelial morphogenesis and the intestine epithelial immune response. Essential for female fertility. Regulates the length and organization of apical microvilli in developing follicle cells and salivary glands. Function in the follicle cell is essential for egg development as the microvilli secrete eggshell material such as the vitelline membrane. Acts at least in part by regulating the recruitment of the myosin ck to the follicle cell microvilli. Also required to regulate cell rearrangements during salivary tube elongation, possibly by modulat [...] | 0.605 |
Cib2 | Myo28B1 | FBpp0293260 | FBpp0079097 | Calcium and integrin binding family member 2; Calcium ion binding; calcium-dependent protein serine/threonine phosphatase activity. It is involved in the biological process described with: calcium ion homeostasis; phototransduction. | Myosin 28B1 (Myo28B1) encodes a high duty ratio motor protein belonging to the MyTH4-FERM subgroup of actin-based molecular motors; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.830 |
Cib2 | ck | FBpp0293260 | FBpp0310275 | Calcium and integrin binding family member 2; Calcium ion binding; calcium-dependent protein serine/threonine phosphatase activity. It is involved in the biological process described with: calcium ion homeostasis; phototransduction. | Myosin-VIIa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements: can function in cells as a single-molecule cargo transporter. A very slow and high-duty-ratio motor, may be suitable for tension maintenance of actin filaments. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Plays a key role in the formation of cellular projections and other actin-based functions required for embryonic and larval viability. Necessary for auditory transduction: [...] | 0.889 |