STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG9084Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (281 aa)    
Predicted Functional Partners:
Tsp42Er
Tetraspanin.
   
    0.715
sphe
Spheroide (sphe) encodes a serine protein homologue, a serine protease with no catalytic activity.
   
    0.660
CG42825
GH19118p; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport.
   
    0.632
CG15044
RE30049p.
   
    0.629
CG12780
CG12780 protein; Carbohydrate binding. It is involved in the biological process described with: defense response to virus; detection of biotic stimulus.
   
 
 0.616
CG10086
RE33762p; It is involved in the biological process described with: protein transport.
   
    0.611
CG42335
Aminopeptidase; Peptide binding; zinc ion binding; metalloaminopeptidase activity. It is involved in the biological process described with: peptide catabolic process; proteolysis.
   
    0.611
CG33331
Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane.
      
 0.604
CG13488
Uncharacterized protein, isoform C.
   
    0.580
alpha-Est2
Alpha-Esterase-2, isoform A; Carboxylic ester hydrolase activity.
   
  
 0.555
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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