STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PgkPhosphoglycerate kinase (Pgk) encodes an enzyme involved in myoblast fusion; Belongs to the phosphoglycerate kinase family. (415 aa)    
Predicted Functional Partners:
Eno
Enolase (Eno) encodes a phosphopyruvate hydratase involved in glucose homeostasis; Belongs to the enolase family.
  
 
 0.999
Tpi
Triose phosphate isomerase (Tpi) encodes a soluble metabolic protein dimer that functions in glycolysis catalyzing the isomerization between dihydroxyacetone phosphate and glyceraldehyde 3-phosphate, which is essential for efficient ATP production.
 
 
 0.999
Gapdh1
Glyceraldehyde 3 phosphate dehydrogenase 1 (Gapdh1) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glycolysis, myoblast fusion and the development of somatic muscle.
 
 0.998
Gapdh2
Glyceraldehyde 3 phosphate dehydrogenase 2 (Gapdh2) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glucose homeostasis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 0.997
Pglym78
Phosphoglyceromutase 78 (Pglym78) encodes an enzyme involved in myoblast fusion and somatic muscle development; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
   
 0.997
Pglym87
Phosphoglycerate mutase activity. It is involved in the biological process described with: glycolytic process; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
   
 0.992
Pgi
Phosphoglucose isomerase (Pgi) encodes an enzyme involved in glucose homeostasis.
  
 
 0.992
PyK
Pyruvate kinase (PyK) encodes an enzyme involved in muscle development, glycolysis and glucose homeostasis; Belongs to the pyruvate kinase family.
  
 
 0.991
CG9010
Glyceraldehyde-3-phosphate dehydrogenase; Peptidyl-cysteine S-nitrosylase activity; NADP binding; NAD binding; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. It is involved in the biological process described with: oxidation-reduction process; glycolytic process; glucose metabolic process.
 
 0.991
CG7059
Phosphoglycerate mutase activity. It is involved in the biological process described with: glycolytic process; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
   
 0.987
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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