STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG16758Uncharacterized protein, isoform H; Purine-nucleoside phosphorylase activity. It is involved in the biological process described with: nucleoside metabolic process. (396 aa)    
Predicted Functional Partners:
CG18128
FI08065p; Purine-nucleoside phosphorylase activity. It is involved in the biological process described with: nucleoside metabolic process.
  
  
 
0.810
Pif1B
PFTAIRE-interacting factor 1B, isoform A; Protein binding.
   
  
 0.675
Dmtn
Dementin, isoform H; Dementin (Dmtn) encodes a protein that possesses an evolutionarily conserved interaction with members of the Amyloid beta A4 protein family. Co-expression of Dmtn rescues the effect of over-expressing human Amyloid beta A4 protein on development and behavior, and mutation of Dmtn causes aberrant processing of the product of Appl.
      
 0.664
Nep5
Neprilysin 5, isoform D; Metallopeptidase activity; metalloendopeptidase activity. It is involved in the biological process described with: proteolysis.
      
 0.626
SCaMC
Short Calcium-binding Mitochondrial Carrier (SCaMC) encodes a mitochondrial carrier family protein with calcium-binding motifs. SCaMC transcripts are strongly detected in the corpora allata, suggesting its potential role in juvenile hormone biosynthesis.
      
 0.626
CG4502
Ubiquitin-conjugating enzyme E2Q-like protein CG4502; Catalyzes the covalent attachment of ubiquitin to other proteins.
   
  
 0.610
CG32425
LD41948p.
      
 0.608
Svil
Supervillin, isoform AE; Actin filament binding. It is involved in the biological process described with: actin polymerization or depolymerization.
      
 0.608
Gk2
Glycerol kinase activity; phosphotransferase activity, alcohol group as acceptor. It is involved in the biological process described with: glycerol metabolic process; glycerol-3-phosphate biosynthetic process; triglyceride metabolic process; phosphorylation.
   
  
 0.608
Fbl6
F-box and leucine-rich repeat protein 6, isoform A; SAM domain binding. It is involved in the biological process described with: positive regulation of ubiquitin-dependent protein catabolic process; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; regulation of protein stability; ubiquitin-dependent protein catabolic process.
      
 0.606
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.