STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
qkr54BQuaking related 54B, isoform E; mRNA binding; RNA binding. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome. (617 aa)    
Predicted Functional Partners:
CG4612
LD36772p; poly(U) RNA binding; mRNA 3'-UTR binding; mRNA binding; poly(A) binding; RNA binding. It is involved in the biological process described with: long-term memory; positive regulation of translation.
   
 
 0.732
qkr58E-2
Quaking related 58E-2, isoform A; mRNA binding. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome.
  
0.714
qkr58E-3
Quaking related 58E-3 (qkr58E-3) encodes an RNA binding protein that contributes to mRNA splicing and apoptosis.
  
 
0.710
CG7903
Uncharacterized protein, isoform A; Nucleic acid binding; mRNA binding.
    
 
 0.674
CG6701
Uncharacterized protein, isoform B; RNA binding. It is involved in the biological process described with: posttranscriptional gene silencing by RNA; dendrite morphogenesis.
   
 
 0.644
CG6227
LD41277p; ATP binding; RNA helicase activity; RNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome; regulation of alternative mRNA splicing, via spliceosome.
    
 
 0.623
nito
RNA-binding protein spenito; RNA-binding protein that acts as an associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs. M6a modification plays a role in the efficiency of mRNA splicing and is required for sex determination. In the WMM complex, may act by binding target RNAs and recruiting the WMM complex. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physi [...]
   
 
 0.580
Syp
Syncrip, isoform J; Syncrip (Syp) encodes an RNA-binding protein that regulates the localization and translation of mRNAs involved in multiple processes. It is required for synapse morphology and synaptic transmission at the neuromuscular junction as well as being involved in oocyte axis specification and control of neuronal cell fates in the mushroom body.
   
 
 0.554
snRNP-U1-70K
Small ribonucleoprotein particle U1 subunit 70K (snRNP-U1-70K) encodes a protein component of the U1 snRNP. The U1 snRNP combines with other snRNPs on the pre-mRNA to assemble a spliceosome.
   
 
 0.552
CG10384
IP21806p; mRNA binding. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome.
  
  
0.543
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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