STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG43780GEO05642p1. (162 aa)    
Predicted Functional Partners:
udt
LD32918p; It is involved in the biological process described with: wound healing.
   
    0.750
pck
EG:80H7.2 protein; Pickel (pck) encodes a transmembrane protein of the Claudin superfamily. It is part of the septate junction (SJ) core complex and essential for SJ morphogenesis and function. The transepithelial barrier function of epithelial tissues is affected in pck mutants.
   
   0.596
pasi2
Pasiflora 2 (pasi2) encodes a septate junction protein involved in endothelial barrier function.
   
    0.554
sinu
Sinuous (sinu) encodes a claudin that contributes to the assembly of septate junctions. It is involved in the development of heart, tracheal tree and the glial blood-brain barrier.
   
   0.545
kune
Kune-kune; It is involved in the biological process described with: establishment of glial blood-brain barrier; regulation of tube length, open tracheal system; septate junction assembly.
   
   0.542
Tsf2
Transferrin 2 (Tsf2) encodes a protein that requires binding with iron for protein function. It is localised at the paracellular septate junctions in epithelial tissues and is required for junction assembly. Tsf2 mutants show overelongated tracheal tubes.
   
    0.481
CG4455
GEO06505p1.
   
    0.473
Cont
Contactin; Required for organization of septate junctions and paracellular barrier functions. Septate junctions, which are the equivalent of vertebrates tight junctions, are characterized by regular arrays of transverse structures that span the intermembrane space and form a physical barrier to diffusion.
   
    0.463
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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