STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
atkArtichoke (atk) encodes a leucine-rich-repeat extracellular matrix protein secreted by accessory cells in ciliated sensory organs. It surrounds the tip of the cilium, and contributes to its assembly. Its roles include cilium integrity, chemosensation and proprioception. (1535 aa)    
Predicted Functional Partners:
CG7800
FI02011p.
    
 
0.722
Cirl
Latrophilin Cirl; Latrotoxin receptor activity; G protein-coupled receptor activity; carbohydrate binding; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    
   0.636
CG6749
LP04042p.
  
 
 
0.539
Lrt
Leucine-rich tendon-specific protein (Lrt) encodes a transmembrane protein expressed specifically in tendon cells. It binds to the product of robo1 and is required for proper patterning of the muscles.
  
 
 
0.528
CG32055
Uncharacterized protein.
  
 
 
0.507
CG3494
Uncharacterized protein, isoform A.
  
   0.488
CG11099
RH62264p.
  
     0.487
Lrch
Leucine-rich-repeats and calponin homology domain protein (Lrch) encodes a scaffold protein well conserved across animals that associates with actin-rich structures during cell division. Lack of Lrch results in a reduction of fertility and fitness.
  
 
   0.471
CG13708
Uncharacterized protein, isoform A.
  
     0.460
CG3408
RE10106p.
  
     0.455
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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