Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| 5-HT2A | Deaf1 | FBpp0078495 | FBpp0304463 | 5-hydroxytryptamine (serotonin) receptor 2A (5-HT2A) encodes a 5-hydroxytryptamine (serotonin) GPCR that belongs to the Class A GPCR family. They bind and transmit the signal from the neurotransmitter 5-HT (serotonin). The family can be subdivided into several subclasses based on pharmacology, signal transduction and structure. There are 5 genes encoding serotonin receptors in the Drosophila melanogaster genome: 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2B, and 5-HT7. | Deformed epidermal autoregulatory factor 1; Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd. | 0.538 |
| CG2926 | Deaf1 | FBpp0078401 | FBpp0304463 | Uncharacterized protein, isoform A; Zinc ion binding. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome. | Deformed epidermal autoregulatory factor 1; Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd. | 0.524 |
| CG4360 | Deaf1 | FBpp0083307 | FBpp0304463 | Uncharacterized protein, isoform A; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific. It is involved in the biological process described with: negative regulation of transcription by RNA polymerase II. | Deformed epidermal autoregulatory factor 1; Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd. | 0.528 |
| CG8569 | Deaf1 | FBpp0087051 | FBpp0304463 | LD16826p; Methylated histone binding. | Deformed epidermal autoregulatory factor 1; Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd. | 0.552 |
| Deaf1 | 5-HT2A | FBpp0304463 | FBpp0078495 | Deformed epidermal autoregulatory factor 1; Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd. | 5-hydroxytryptamine (serotonin) receptor 2A (5-HT2A) encodes a 5-hydroxytryptamine (serotonin) GPCR that belongs to the Class A GPCR family. They bind and transmit the signal from the neurotransmitter 5-HT (serotonin). The family can be subdivided into several subclasses based on pharmacology, signal transduction and structure. There are 5 genes encoding serotonin receptors in the Drosophila melanogaster genome: 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2B, and 5-HT7. | 0.538 |
| Deaf1 | CG2926 | FBpp0304463 | FBpp0078401 | Deformed epidermal autoregulatory factor 1; Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd. | Uncharacterized protein, isoform A; Zinc ion binding. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome. | 0.524 |
| Deaf1 | CG4360 | FBpp0304463 | FBpp0083307 | Deformed epidermal autoregulatory factor 1; Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd. | Uncharacterized protein, isoform A; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific. It is involved in the biological process described with: negative regulation of transcription by RNA polymerase II. | 0.528 |
| Deaf1 | CG8569 | FBpp0304463 | FBpp0087051 | Deformed epidermal autoregulatory factor 1; Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd. | LD16826p; Methylated histone binding. | 0.552 |
| Deaf1 | Dfd | FBpp0304463 | FBpp0081138 | Deformed epidermal autoregulatory factor 1; Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd. | Homeotic protein deformed; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Homeotic protein controlling Drosophila head development. Transcriptional activator of the apoptotic activator protein rpr in cells at the maxillary/mandibular boundary; Belongs to the Antp homeobox family. Deformed subfamily. | 0.780 |
| Deaf1 | Helz | FBpp0304463 | FBpp0075443 | Deformed epidermal autoregulatory factor 1; Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd. | Uncharacterized protein, isoform B; RNA binding; metal ion binding. It is involved in the biological process described with: posttranscriptional gene silencing by RNA. | 0.560 |
| Deaf1 | Pli | FBpp0304463 | FBpp0111820 | Deformed epidermal autoregulatory factor 1; Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd. | Pellino (Pli) encodes a RING-domain-containing ubiquitin E3 ligase that coordinates with ubiquitin-activating (E1) and ubiquitin-conjugating (E2) enzymes to degrade target proteins. It functions as a negative regulator of the Toll-mediated innate immunity pathway. | 0.573 |
| Deaf1 | Smyd4-2 | FBpp0304463 | FBpp0075717 | Deformed epidermal autoregulatory factor 1; Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd. | SET and MYND domain containing, class 4, member 2 (Smyd4-2) encodes a histone deacetylase involved in photoreceptor development, eclosion, and gene expression regulation. | 0.533 |
| Deaf1 | Smyd5 | FBpp0304463 | FBpp0083507 | Deformed epidermal autoregulatory factor 1; Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd. | SET and MYND domain containing, class 5; S-adenosylmethionine-dependent methyltransferase activity. It is involved in the biological process described with: histone lysine methylation. | 0.558 |
| Deaf1 | cactin | FBpp0304463 | FBpp0309346 | Deformed epidermal autoregulatory factor 1; Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd. | Cactin; Plays a role during early embryonic development. Involved in the dorsal-ventral embryonic patterning. Probably acts as a negative regulator of the NF-kappa-B (Rel) signaling pathway. Belongs to the CACTIN family. | 0.584 |
| Dfd | Deaf1 | FBpp0081138 | FBpp0304463 | Homeotic protein deformed; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Homeotic protein controlling Drosophila head development. Transcriptional activator of the apoptotic activator protein rpr in cells at the maxillary/mandibular boundary; Belongs to the Antp homeobox family. Deformed subfamily. | Deformed epidermal autoregulatory factor 1; Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd. | 0.780 |
| Helz | Deaf1 | FBpp0075443 | FBpp0304463 | Uncharacterized protein, isoform B; RNA binding; metal ion binding. It is involved in the biological process described with: posttranscriptional gene silencing by RNA. | Deformed epidermal autoregulatory factor 1; Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd. | 0.560 |
| Helz | Smyd4-2 | FBpp0075443 | FBpp0075717 | Uncharacterized protein, isoform B; RNA binding; metal ion binding. It is involved in the biological process described with: posttranscriptional gene silencing by RNA. | SET and MYND domain containing, class 4, member 2 (Smyd4-2) encodes a histone deacetylase involved in photoreceptor development, eclosion, and gene expression regulation. | 0.607 |
| Helz | Smyd5 | FBpp0075443 | FBpp0083507 | Uncharacterized protein, isoform B; RNA binding; metal ion binding. It is involved in the biological process described with: posttranscriptional gene silencing by RNA. | SET and MYND domain containing, class 5; S-adenosylmethionine-dependent methyltransferase activity. It is involved in the biological process described with: histone lysine methylation. | 0.699 |
| Pli | Deaf1 | FBpp0111820 | FBpp0304463 | Pellino (Pli) encodes a RING-domain-containing ubiquitin E3 ligase that coordinates with ubiquitin-activating (E1) and ubiquitin-conjugating (E2) enzymes to degrade target proteins. It functions as a negative regulator of the Toll-mediated innate immunity pathway. | Deformed epidermal autoregulatory factor 1; Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd. | 0.573 |
| Pli | cactin | FBpp0111820 | FBpp0309346 | Pellino (Pli) encodes a RING-domain-containing ubiquitin E3 ligase that coordinates with ubiquitin-activating (E1) and ubiquitin-conjugating (E2) enzymes to degrade target proteins. It functions as a negative regulator of the Toll-mediated innate immunity pathway. | Cactin; Plays a role during early embryonic development. Involved in the dorsal-ventral embryonic patterning. Probably acts as a negative regulator of the NF-kappa-B (Rel) signaling pathway. Belongs to the CACTIN family. | 0.799 |
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