STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppk30Pickpocket 30, isoform A; Sodium channel activity. It is involved in the biological process described with: sodium ion transport; regulation of terminal button organization; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (457 aa)    
Predicted Functional Partners:
ppk25
Pickpocket 25 (ppk25) encodes a DEG/ENaC channel subunit involved in male courtship behavior and pheromone detection; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.662
CG2258
LD35927p; Myosin binding.
   
  
 0.627
ppk17
Pickpocket 17, isoform A; Sodium channel activity. It is involved in the biological process described with: sodium ion transport; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.609
X11Lbeta
X11Lbeta, isoform A; It is involved in the biological process described with: protein localization to membrane; chemical synaptic transmission.
      
 0.603
ppk9
Pickpocket 9, isoform A; Sodium channel activity. It is involved in the biological process described with: sodium ion transport; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.600
CG6048
FI06405p; Serine-type endopeptidase activity. It is involved in the biological process described with: regulation of terminal button organization; proteolysis.
      
 0.542
ppk22
Pickpocket 22, isoform B; Sodium channel activity. It is involved in the biological process described with: sodium ion transport; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
   
  
 0.533
chif
Chiffon (chif) encodes a protein associated with the origin recognition complex that binds to chromosomal origins of replication and is required for the initiation of cellular DNA replication. It is involved in DNA replication, chorion production, muscle homeostasis, and axon guidance.
      
 0.497
CG43795
G_PROTEIN_RECEP_F3_4 domain-containing protein; G protein-coupled receptor activity. It is involved in the biological process described with: G protein-coupled receptor signaling pathway.
      
 0.497
NaPi-T
Na[+]-dependent inorganic phosphate cotransporter, isoform A; Phosphate ion transmembrane transporter activity; transmembrane transporter activity. It is involved in the biological process described with: phosphate ion transmembrane transport; anion transport.
      
 0.493
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.