STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG12081LD20420p; Chromatin binding. (403 aa)    
Predicted Functional Partners:
EloB
Elongin B (EloB) encodes an essential protein for development that participates in the control of wing cell identity. EloB, EloC and EloA encode for subunits of the Elongin complex, which interacts in vivo with the chromatin factor encoded by corto.
    
 
 0.718
mxt
Eukaryotic translation initiation factor 4E-binding protein Mextli; Mextli (mxt) encodes a protein that promotes translation. It binds to the products of eIF4E1 and eIF3h. It contributes to maintenance of germline stem cells and it is also involved in early embryogenesis.
 
      0.696
Cul2
Cullin 2 (Cul2) encodes a protein that plays important roles during oogenesis. Reduction of the product of Cul2 in somatic cells produces tumorous germaria with excess germline stem cell-like cells due to the elevation of Dpp signaling in the niche; Belongs to the cullin family.
    
 
 0.661
EloC
Elongin C (EloC) encodes an essential protein for development that participates in the control of wing cell identity. EloB, EloC and EloA encode for subunits of the Elongin complex, which interacts in vivo with the chromatin factor encoded by corto.
    
   0.630
Zmynd10
Zinc finger MYND domain-containing protein 10 homolog; Plays a role in axonemal structure organization and motility. May be involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility; Belongs to the ZMYND10 family.
      
 0.504
CG16721
LD23868p; It is involved in the biological process described with: cAMP-mediated signaling; signal transduction.
   
  
 0.446
mRpL2
Mitochondrial ribosomal protein L2; RNA binding; structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation.
   
  
 0.441
dysf
Dysfusion, isoform D; Dysfusion (dysf) encodes a transcription factor that forms a DNA binding complex with the product of tgo to activate target genes. It is involved in in migration, adhesion, and fusion of tracheal cells, as well as tarsal joint formation during leg development.
 
    
 0.424
PhKgamma
Phosphorylase kinase gamma (PhKgamma) encodes a protein involved in gastrulation, embryonic mesoderm formation and adult leg musculature development.
      
 0.407
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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