STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Oseg2Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia. Belongs to the IFT172 family. (1754 aa)    
Predicted Functional Partners:
IFT52
Intraflagellar transport 52.
   
 0.995
Ttc30
Tetratricopeptide repeat protein 30 homolog; Required for polyglutamylation of axonemal tubulin in sensory cilia. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip; Belongs to the TTC30/dfy-1/fleer family.
   
 0.995
IFT57
Intraflagellar transport protein 57 homolog; Required for the formation of cilia; Belongs to the IFT57 family.
   
 0.994
nompB
No mechanoreceptor potential B (nompB) encodes an essential component of the conserved intraflagellar transport mechanism, which is needed to extend cilia above the cell surface. nompB mutants have truncated, nonfunctional sensory cilia with consequent mechanosensory deficits.
   
 0.993
Oseg5
Outer segment 5; It is involved in the biological process described with: non-motile cilium assembly; cilium assembly.
   
 0.990
Oseg1
Outer segment 1 (Oseg1) encodes a protein required for ciliogenesis.
   
 0.985
Cluap1
Clusterin associated protein 1; It is involved in the biological process described with: cilium assembly.
   
 0.981
IFT54
Intraflagellar transport 54; Microtubule binding. It is involved in the biological process described with: regulation of microtubule cytoskeleton organization; intraciliary transport; cilium assembly.
   
 0.981
Ttc26
Tetratricopeptide repeat domain 26; Intraciliary transport particle B binding. It is involved in the biological process described with: cilium assembly; intraciliary anterograde transport; intraciliary transport involved in cilium assembly.
   
 0.971
IFT46
Intraflagellar transport 46; It is involved in the biological process described with: intraciliary transport; cilium assembly.
   
 0.968
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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