STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cyp312a1Probable cytochrome P450 312a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. (510 aa)    
Predicted Functional Partners:
CG12229
AT14039p; Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: glycolytic process; pyruvate biosynthetic process.
   
 
 0.611
Acp26Aa
Accessory gland protein 26Aa (Acp26Aa) encodes a protein synthesized in male accessory glands. It is transferred during mating to females where it induces an increase in ovulation by relaxing the oviduct via activation of octopaminergic signaling.
   
    0.611
spok
Spookier (spok) encodes a cytochrome P450 involved in ecdysteroid biosynthesis that is expressed primarily in the prothoracic gland and is localized in the endoplasmic reticulum. Genetic evidence suggests that the product of spok acts with the products of sro and Cyp6t3 to catalyze conversion of 7 dehydrocholesterol to delta4, diketol during the ecdysone biosynthetic pathway.
  
 
 0.569
Acp26Ab
Accessory gland protein 26Ab (Acp26Ab) encodes a peptide that is produced by male accessory glands and transferred to females during mating.
   
    0.567
CG6168
Uncharacterized protein, isoform B; CG6168 encodes a predicted metalloendopeptidase that is produced by the male accessory glands. CG6168 ectopic expression in females provides anti-microbial protection.
   
    0.567
Spn38F
Serpin 38F (Spn38F) encodes a predicted serine endopeptidase inhibitor. It is expressed in the male accessory glands and transferred to females during mating. Spn38F ectopic expression in females provides anti-microbial protection.
   
    0.565
Spn28F
Serpin 28F (Spn28F) encodes a predicted serine protease inhibitor. It is expressed in the male accessory glands and transferred to females during mating.
   
    0.558
CG6149
Uncharacterized protein.
   
    0.530
Acp53C14a
Accessory gland protein 53C14a, isoform A; It is involved in the biological process described with: multicellular organism reproduction.
   
    0.530
CG15635
Uncharacterized protein; It is involved in the biological process described with: multicellular organism reproduction.
   
   0.529
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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