STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG3919Uncharacterized protein, isoform C; DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. (318 aa)    
Predicted Functional Partners:
CG1602
LD33878p; Sequence-specific DNA binding. It is involved in the biological process described with: regulation of gene expression; positive regulation of transcription, DNA-templated; regulation of transcription, DNA-templated.
   
  
 0.912
CG13204
FI20150p1; CG13204 encodes a protein predicted to be a transcriptional regulator. CG13204 overexpression can partially rescue hng1 loss of function, suggesting either epistasis or an overlaping function between hng1 and CG13204.
      
 0.911
CG1603
FI01116p; Transcription coactivator activity; nucleic acid binding. It is involved in the biological process described with: regulation of gene expression; positive regulation of transcription by RNA polymerase II.
   
  
 0.840
az2
RE20796p; RNA polymerase II regulatory region sequence-specific DNA binding; sequence-specific DNA binding; zinc ion binding; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated.
   
  
 0.837
hng2
LD09733p; DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II.
   
  
 0.681
red
Red malpighian tubules, isoform B.
      
 0.446
hng1
CG9437 protein; DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II.
      
 0.400
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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