STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hfwProtein halfway; Has a role in the ecdysone induced cascade; probably indirect control of 'late' ecdysone genes. (611 aa)    
Predicted Functional Partners:
CG3795
GH24985p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
    
 
 0.836
dor
Vacuolar protein sorting-associated protein 18 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes probably as part of the class C core vacuole/endosome tethering (CORVET) complex. In larval neuromuscular junctions, essential for endosomal sorting which traffics old or dysfunctional synaptic vesicle proteins through a degradative endolysosomal route. Required for the biogenesis of eye pigment granules. Required to maintain normal levels of rush, which functions in endosome formation [...]
 
    
 0.803
CG14797
CG14797-PA.
      
 0.680
CG3740
GEO08311p1; It is involved in the biological process described with: neuromuscular process.
      
 0.675
PhKgamma
Phosphorylase kinase gamma (PhKgamma) encodes a protein involved in gastrulation, embryonic mesoderm formation and adult leg musculature development.
   
  
 0.664
Cirl
Latrophilin Cirl; Latrotoxin receptor activity; G protein-coupled receptor activity; carbohydrate binding; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    
   0.636
Mur2B
Mucin related 2B, isoform A; Extracellular matrix structural constituent; chitin binding. It is involved in the biological process described with: chitin metabolic process.
    
 
 0.631
Nipsnap
Protein NipSnap; Belongs to the NipSnap family.
   
  
 0.614
b6
FBgn0024897;b6 protein (Eg:9d2.1 protein).
  
 
 
 0.527
CG43218
MIP12702p; Chitin binding. It is involved in the biological process described with: chitin metabolic process.
    
 
 0.521
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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