Lcp1 protein (Drosophila melanogaster) - STRING interaction network

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Lcp1

Larval cuticle protein 1; Component of the larval cuticle. (130 aa)

Predicted Functional Partners:

Mdr65

0.663

Cyp4g1

0.632

Mdr50

0.609

Cyp12d1-p

0.607

MRP

0.606

CG42500

0.604

Bap60

0.587

polybromo

0.587

Snr1

0.584

mor

0.584

Your Current Organism:

Drosophila melanogaster

NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bap60	Lcp1	FBpp0073572	FBpp0305735	Brahma-associated protein of 60 kDa; Involved in the recruitment and site-specific anchoring of the Brahma complex at specific promoter sites. The Brahma complex is a multiprotein complex which is the equivalent of the yeast SWI/SNF complex and acts by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. This complex can both serve as a transcriptional coactivator or corepressor, depending on the context. Participates in X-chromosomal dosage compensation. Participates in neurogenesis.	Larval cuticle protein 1; Component of the larval cuticle.	0.587
Bap60	Snr1	FBpp0073572	FBpp0078331	Brahma-associated protein of 60 kDa; Involved in the recruitment and site-specific anchoring of the Brahma complex at specific promoter sites. The Brahma complex is a multiprotein complex which is the equivalent of the yeast SWI/SNF complex and acts by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. This complex can both serve as a transcriptional coactivator or corepressor, depending on the context. Participates in X-chromosomal dosage compensation. Participates in neurogenesis.	Snf5-related 1 (Snr1) encodes a core component of the ATP-dependent SWI/SNF chromatin-remodeling complex (Brahma complex). It functions as a tumor suppressor and is required for maintaining normal endosomal trafficking-mediated signaling cascades; Belongs to the SNF5 family.	0.999
Bap60	mor	FBpp0073572	FBpp0082692	Brahma-associated protein of 60 kDa; Involved in the recruitment and site-specific anchoring of the Brahma complex at specific promoter sites. The Brahma complex is a multiprotein complex which is the equivalent of the yeast SWI/SNF complex and acts by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. This complex can both serve as a transcriptional coactivator or corepressor, depending on the context. Participates in X-chromosomal dosage compensation. Participates in neurogenesis.	Brahma associated protein 155 kDa; Moira (mor) encodes a member of the trithorax group of homeotic gene regulators. The product of mor is a chromatin remodeling protein and functions as the Swi3 component of the Brahma complex.	0.999
Bap60	polybromo	FBpp0073572	FBpp0084115	Brahma-associated protein of 60 kDa; Involved in the recruitment and site-specific anchoring of the Brahma complex at specific promoter sites. The Brahma complex is a multiprotein complex which is the equivalent of the yeast SWI/SNF complex and acts by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. This complex can both serve as a transcriptional coactivator or corepressor, depending on the context. Participates in X-chromosomal dosage compensation. Participates in neurogenesis.	Polybromo (polybromo) encodes a subunit of Polybromo-associated Brahma complex (PBAP). Its main biological role is involved in chromatin remodeling together with Brahma complex. It can also regulate gene transcription through DNA binding, which is dependent or independent ofthe PBAP complex.	0.999
CG42500	Lcp1	FBpp0307925	FBpp0305735	Uncharacterized protein, isoform A.	Larval cuticle protein 1; Component of the larval cuticle.	0.604
Cyp12d1-p	Cyp4g1	FBpp0311725	FBpp0070094	Probable cytochrome P450 12d1 proximal, mitochondrial; Cyp12d1-p (Cyp12d1-p) encodes a protein involved in the response to the insecticide dichlorodiphenyltrichloroethane (DDT).	Cytochrome P450-4g1 (Cyp4g1) encodes the terminal oxidative decarbonylase in cuticular hydrocarbon biosynthesis within oenocytes.	0.458
Cyp12d1-p	Lcp1	FBpp0311725	FBpp0305735	Probable cytochrome P450 12d1 proximal, mitochondrial; Cyp12d1-p (Cyp12d1-p) encodes a protein involved in the response to the insecticide dichlorodiphenyltrichloroethane (DDT).	Larval cuticle protein 1; Component of the larval cuticle.	0.607
Cyp12d1-p	MRP	FBpp0311725	FBpp0089070	Probable cytochrome P450 12d1 proximal, mitochondrial; Cyp12d1-p (Cyp12d1-p) encodes a protein involved in the response to the insecticide dichlorodiphenyltrichloroethane (DDT).	Multidrug-Resistance like protein 1, isoform A; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase-coupled inorganic anion transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; anion transmembrane transport.	0.523
Cyp12d1-p	Mdr50	FBpp0311725	FBpp0086666	Probable cytochrome P450 12d1 proximal, mitochondrial; Cyp12d1-p (Cyp12d1-p) encodes a protein involved in the response to the insecticide dichlorodiphenyltrichloroethane (DDT).	Multi drug resistance 50; Efflux transmembrane transporter activity; ATPase-coupled xenobiotic transmembrane transporter activity; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: response to insecticide; response to toxic substance; xenobiotic transport; transmembrane transport; renal tubular secretion.	0.526
Cyp12d1-p	Mdr65	FBpp0311725	FBpp0076719	Probable cytochrome P450 12d1 proximal, mitochondrial; Cyp12d1-p (Cyp12d1-p) encodes a protein involved in the response to the insecticide dichlorodiphenyltrichloroethane (DDT).	Multidrug resistance protein homolog 65; Multi drug resistance 65 (Mdr65) encodes a member of the MRP/ABCC subfamily of ATP-binding cassette (ABC) transporters. It is involved in humoral/CNS barrier drug exclusion and response to insecticide; Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.	0.550
Cyp4g1	Cyp12d1-p	FBpp0070094	FBpp0311725	Cytochrome P450-4g1 (Cyp4g1) encodes the terminal oxidative decarbonylase in cuticular hydrocarbon biosynthesis within oenocytes.	Probable cytochrome P450 12d1 proximal, mitochondrial; Cyp12d1-p (Cyp12d1-p) encodes a protein involved in the response to the insecticide dichlorodiphenyltrichloroethane (DDT).	0.458
Cyp4g1	Lcp1	FBpp0070094	FBpp0305735	Cytochrome P450-4g1 (Cyp4g1) encodes the terminal oxidative decarbonylase in cuticular hydrocarbon biosynthesis within oenocytes.	Larval cuticle protein 1; Component of the larval cuticle.	0.632
Cyp4g1	MRP	FBpp0070094	FBpp0089070	Cytochrome P450-4g1 (Cyp4g1) encodes the terminal oxidative decarbonylase in cuticular hydrocarbon biosynthesis within oenocytes.	Multidrug-Resistance like protein 1, isoform A; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase-coupled inorganic anion transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; anion transmembrane transport.	0.468
Cyp4g1	Mdr50	FBpp0070094	FBpp0086666	Cytochrome P450-4g1 (Cyp4g1) encodes the terminal oxidative decarbonylase in cuticular hydrocarbon biosynthesis within oenocytes.	Multi drug resistance 50; Efflux transmembrane transporter activity; ATPase-coupled xenobiotic transmembrane transporter activity; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: response to insecticide; response to toxic substance; xenobiotic transport; transmembrane transport; renal tubular secretion.	0.578
Cyp4g1	Mdr65	FBpp0070094	FBpp0076719	Cytochrome P450-4g1 (Cyp4g1) encodes the terminal oxidative decarbonylase in cuticular hydrocarbon biosynthesis within oenocytes.	Multidrug resistance protein homolog 65; Multi drug resistance 65 (Mdr65) encodes a member of the MRP/ABCC subfamily of ATP-binding cassette (ABC) transporters. It is involved in humoral/CNS barrier drug exclusion and response to insecticide; Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.	0.564
Lcp1	Bap60	FBpp0305735	FBpp0073572	Larval cuticle protein 1; Component of the larval cuticle.	Brahma-associated protein of 60 kDa; Involved in the recruitment and site-specific anchoring of the Brahma complex at specific promoter sites. The Brahma complex is a multiprotein complex which is the equivalent of the yeast SWI/SNF complex and acts by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. This complex can both serve as a transcriptional coactivator or corepressor, depending on the context. Participates in X-chromosomal dosage compensation. Participates in neurogenesis.	0.587
Lcp1	CG42500	FBpp0305735	FBpp0307925	Larval cuticle protein 1; Component of the larval cuticle.	Uncharacterized protein, isoform A.	0.604
Lcp1	Cyp12d1-p	FBpp0305735	FBpp0311725	Larval cuticle protein 1; Component of the larval cuticle.	Probable cytochrome P450 12d1 proximal, mitochondrial; Cyp12d1-p (Cyp12d1-p) encodes a protein involved in the response to the insecticide dichlorodiphenyltrichloroethane (DDT).	0.607
Lcp1	Cyp4g1	FBpp0305735	FBpp0070094	Larval cuticle protein 1; Component of the larval cuticle.	Cytochrome P450-4g1 (Cyp4g1) encodes the terminal oxidative decarbonylase in cuticular hydrocarbon biosynthesis within oenocytes.	0.632
Lcp1	MRP	FBpp0305735	FBpp0089070	Larval cuticle protein 1; Component of the larval cuticle.	Multidrug-Resistance like protein 1, isoform A; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase-coupled inorganic anion transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; anion transmembrane transport.	0.606