node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG7639 | CG9393 | FBpp0086555 | FBpp0081591 | SAM50-like protein CG7639; May play a role in the maintenance of the structure of mitochondrial cristae; Belongs to the SAM50/omp85 family. | Metaxin-1 homolog; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity); Belongs to the metaxin family. | 0.995 |
CG7639 | Tom20 | FBpp0086555 | FBpp0304965 | SAM50-like protein CG7639; May play a role in the maintenance of the structure of mitochondrial cristae; Belongs to the SAM50/omp85 family. | Translocase of outer membrane 20, isoform A; Mitochondrion targeting sequence binding; P-P-bond-hydrolysis-driven protein transmembrane transporter activity. It is involved in the biological process described with: protein targeting to mitochondrion; tRNA import into mitochondrion; mitochondrial outer membrane translocase complex assembly; protein import into mitochondrial matrix. | 0.757 |
CG7639 | Tom40 | FBpp0086555 | FBpp0305890 | SAM50-like protein CG7639; May play a role in the maintenance of the structure of mitochondrial cristae; Belongs to the SAM50/omp85 family. | Mitochondrial import receptor subunit TOM40 homolog 1; Translocase of outer membrane 40 (Tom40) encodes a protein predicted to be a channel component of the TOM complex, which is involved in protein import into mitochondria. It is predicted to be involved in the cellular response to hypoxia. | 0.926 |
CG7639 | Tom7 | FBpp0086555 | FBpp0308412 | SAM50-like protein CG7639; May play a role in the maintenance of the structure of mitochondrial cristae; Belongs to the SAM50/omp85 family. | Translocase of outer membrane 7 (Tom7) encodes a putative mitochondrial protein that may act as a channel component of the TOM complex based on orthology with the human gene TOMM7. | 0.842 |
CG7639 | Tom70 | FBpp0086555 | FBpp0079895 | SAM50-like protein CG7639; May play a role in the maintenance of the structure of mitochondrial cristae; Belongs to the SAM50/omp85 family. | Translocase of outer membrane 70 (Tom70) encodes a mitochondrial protein that may act as a receptor of the TOM complex based on orthology. TOM complex is involved in protein import into mitochondria. The product of Tom70 modulates cell death induced by the expression of the mouse Bax protein. | 0.837 |
CG7639 | mge | FBpp0086555 | FBpp0073033 | SAM50-like protein CG7639; May play a role in the maintenance of the structure of mitochondrial cristae; Belongs to the SAM50/omp85 family. | Mitochondrial import protein; Maggie (mge) encodes a protein predicted to act as a receptor of the TOM (translocase of outer membrane) complex, which is involved in protein import into mitochondria. The product of mge modulates cell death induced by the expression of the mouse Bax protein. | 0.973 |
CG7639 | porin | FBpp0086555 | FBpp0100039 | SAM50-like protein CG7639; May play a role in the maintenance of the structure of mitochondrial cristae; Belongs to the SAM50/omp85 family. | Voltage-dependent anion-selective channel; Porin (porin) encodes a beta-barrel channel protein localized in the outer membrane of mitochondria that conducts translocation of various ions and metabolites between cytoplasm and mitochondria. It plays roles in mitochondria dynamics and mitophagy, and is ubiquitinated by the E3 ligases encoded by park and Mul1. | 0.542 |
CG7639 | tomboy20 | FBpp0086555 | FBpp0081792 | SAM50-like protein CG7639; May play a role in the maintenance of the structure of mitochondrial cristae; Belongs to the SAM50/omp85 family. | GEO10511p1; P-P-bond-hydrolysis-driven protein transmembrane transporter activity; mitochondrion targeting sequence binding. It is involved in the biological process described with: protein targeting to mitochondrion; protein import into mitochondrial matrix; mitochondrial outer membrane translocase complex assembly; tRNA import into mitochondrion. | 0.755 |
CG9393 | CG7639 | FBpp0081591 | FBpp0086555 | Metaxin-1 homolog; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity); Belongs to the metaxin family. | SAM50-like protein CG7639; May play a role in the maintenance of the structure of mitochondrial cristae; Belongs to the SAM50/omp85 family. | 0.995 |
CG9393 | Tom20 | FBpp0081591 | FBpp0304965 | Metaxin-1 homolog; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity); Belongs to the metaxin family. | Translocase of outer membrane 20, isoform A; Mitochondrion targeting sequence binding; P-P-bond-hydrolysis-driven protein transmembrane transporter activity. It is involved in the biological process described with: protein targeting to mitochondrion; tRNA import into mitochondrion; mitochondrial outer membrane translocase complex assembly; protein import into mitochondrial matrix. | 0.837 |
CG9393 | Tom40 | FBpp0081591 | FBpp0305890 | Metaxin-1 homolog; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity); Belongs to the metaxin family. | Mitochondrial import receptor subunit TOM40 homolog 1; Translocase of outer membrane 40 (Tom40) encodes a protein predicted to be a channel component of the TOM complex, which is involved in protein import into mitochondria. It is predicted to be involved in the cellular response to hypoxia. | 0.953 |
CG9393 | Tom7 | FBpp0081591 | FBpp0308412 | Metaxin-1 homolog; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity); Belongs to the metaxin family. | Translocase of outer membrane 7 (Tom7) encodes a putative mitochondrial protein that may act as a channel component of the TOM complex based on orthology with the human gene TOMM7. | 0.958 |
CG9393 | Tom70 | FBpp0081591 | FBpp0079895 | Metaxin-1 homolog; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity); Belongs to the metaxin family. | Translocase of outer membrane 70 (Tom70) encodes a mitochondrial protein that may act as a receptor of the TOM complex based on orthology. TOM complex is involved in protein import into mitochondria. The product of Tom70 modulates cell death induced by the expression of the mouse Bax protein. | 0.943 |
CG9393 | mge | FBpp0081591 | FBpp0073033 | Metaxin-1 homolog; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity); Belongs to the metaxin family. | Mitochondrial import protein; Maggie (mge) encodes a protein predicted to act as a receptor of the TOM (translocase of outer membrane) complex, which is involved in protein import into mitochondria. The product of mge modulates cell death induced by the expression of the mouse Bax protein. | 0.949 |
CG9393 | tomboy20 | FBpp0081591 | FBpp0081792 | Metaxin-1 homolog; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity); Belongs to the metaxin family. | GEO10511p1; P-P-bond-hydrolysis-driven protein transmembrane transporter activity; mitochondrion targeting sequence binding. It is involved in the biological process described with: protein targeting to mitochondrion; protein import into mitochondrial matrix; mitochondrial outer membrane translocase complex assembly; tRNA import into mitochondrion. | 0.915 |
Pink1 | Tom20 | FBpp0099833 | FBpp0304965 | PTEN-induced putative kinase 1 (Pink1) is the ortholog of human PINK1, a gene mutated in autosomal recessive Parkinson's disease. Pink1 encodes a mitochondrially targeted Ser-Thr kinase. It has been linked to a number of cellular functions including altering mitochondrial dynamics, the autophagic degradation of dysfunctional mitochondria, and the proper function of Complex I of the electron transport chain. | Translocase of outer membrane 20, isoform A; Mitochondrion targeting sequence binding; P-P-bond-hydrolysis-driven protein transmembrane transporter activity. It is involved in the biological process described with: protein targeting to mitochondrion; tRNA import into mitochondrion; mitochondrial outer membrane translocase complex assembly; protein import into mitochondrial matrix. | 0.970 |
Pink1 | Tom40 | FBpp0099833 | FBpp0305890 | PTEN-induced putative kinase 1 (Pink1) is the ortholog of human PINK1, a gene mutated in autosomal recessive Parkinson's disease. Pink1 encodes a mitochondrially targeted Ser-Thr kinase. It has been linked to a number of cellular functions including altering mitochondrial dynamics, the autophagic degradation of dysfunctional mitochondria, and the proper function of Complex I of the electron transport chain. | Mitochondrial import receptor subunit TOM40 homolog 1; Translocase of outer membrane 40 (Tom40) encodes a protein predicted to be a channel component of the TOM complex, which is involved in protein import into mitochondria. It is predicted to be involved in the cellular response to hypoxia. | 0.894 |
Pink1 | Tom7 | FBpp0099833 | FBpp0308412 | PTEN-induced putative kinase 1 (Pink1) is the ortholog of human PINK1, a gene mutated in autosomal recessive Parkinson's disease. Pink1 encodes a mitochondrially targeted Ser-Thr kinase. It has been linked to a number of cellular functions including altering mitochondrial dynamics, the autophagic degradation of dysfunctional mitochondria, and the proper function of Complex I of the electron transport chain. | Translocase of outer membrane 7 (Tom7) encodes a putative mitochondrial protein that may act as a channel component of the TOM complex based on orthology with the human gene TOMM7. | 0.746 |
Pink1 | Tom70 | FBpp0099833 | FBpp0079895 | PTEN-induced putative kinase 1 (Pink1) is the ortholog of human PINK1, a gene mutated in autosomal recessive Parkinson's disease. Pink1 encodes a mitochondrially targeted Ser-Thr kinase. It has been linked to a number of cellular functions including altering mitochondrial dynamics, the autophagic degradation of dysfunctional mitochondria, and the proper function of Complex I of the electron transport chain. | Translocase of outer membrane 70 (Tom70) encodes a mitochondrial protein that may act as a receptor of the TOM complex based on orthology. TOM complex is involved in protein import into mitochondria. The product of Tom70 modulates cell death induced by the expression of the mouse Bax protein. | 0.815 |
Pink1 | mge | FBpp0099833 | FBpp0073033 | PTEN-induced putative kinase 1 (Pink1) is the ortholog of human PINK1, a gene mutated in autosomal recessive Parkinson's disease. Pink1 encodes a mitochondrially targeted Ser-Thr kinase. It has been linked to a number of cellular functions including altering mitochondrial dynamics, the autophagic degradation of dysfunctional mitochondria, and the proper function of Complex I of the electron transport chain. | Mitochondrial import protein; Maggie (mge) encodes a protein predicted to act as a receptor of the TOM (translocase of outer membrane) complex, which is involved in protein import into mitochondria. The product of mge modulates cell death induced by the expression of the mouse Bax protein. | 0.458 |