| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACC | ATPCL | FBpp0087947 | FBpp0289824 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | ATP-citrate synthase; ATP citrate lyase (ATPCL) encodes a protein involved in glucose homeostasis; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. | 0.968 |
| ACC | Acsl | FBpp0087947 | FBpp0305216 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | Acyl-CoA synthetase long-chain, isoform J; Long-chain fatty acid-CoA ligase activity; palmitoyl-CoA ligase activity. | 0.785 |
| ACC | CG12170 | FBpp0087947 | FBpp0078358 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | 3-oxoacyl-[acyl-carrier-protein] synthase activity. It is involved in the biological process described with: fatty acid biosynthetic process; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.882 |
| ACC | CG3961 | FBpp0087947 | FBpp0074844 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | LD09909p; Long-chain fatty acid-CoA ligase activity. It is involved in the biological process described with: fatty acid biosynthetic process; long-chain fatty acid metabolic process. | 0.409 |
| ACC | FASN2 | FBpp0087947 | FBpp0307370 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | Fatty acid synthase 2 (FASN2) encodes an enzyme required for the synthesis of branched/methylated long chain fatty acids that are the precursors of methylated cuticular hydrocarbons. | 0.980 |
| ACC | FASN3 | FBpp0087947 | FBpp0297101 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | Fatty acid synthase 3; Oxidoreductase activity; phosphopantetheine binding; fatty acid synthase activity; hydrolase activity, acting on ester bonds. It is involved in the biological process described with: biosynthetic process. | 0.952 |
| ACC | beg | FBpp0087947 | FBpp0075038 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | Probable malonyl-CoA-acyl carrier protein transacylase, mitochondrial; Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the ACP protein. This suggests the existence of the biosynthesis of fatty acids in mitochondria (By similarity). | 0.978 |
| ATPCL | ACC | FBpp0289824 | FBpp0087947 | ATP-citrate synthase; ATP citrate lyase (ATPCL) encodes a protein involved in glucose homeostasis; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | 0.968 |
| ATPCL | CG12170 | FBpp0289824 | FBpp0078358 | ATP-citrate synthase; ATP citrate lyase (ATPCL) encodes a protein involved in glucose homeostasis; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. | 3-oxoacyl-[acyl-carrier-protein] synthase activity. It is involved in the biological process described with: fatty acid biosynthetic process; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.414 |
| ATPCL | FASN2 | FBpp0289824 | FBpp0307370 | ATP-citrate synthase; ATP citrate lyase (ATPCL) encodes a protein involved in glucose homeostasis; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. | Fatty acid synthase 2 (FASN2) encodes an enzyme required for the synthesis of branched/methylated long chain fatty acids that are the precursors of methylated cuticular hydrocarbons. | 0.952 |
| ATPCL | FASN3 | FBpp0289824 | FBpp0297101 | ATP-citrate synthase; ATP citrate lyase (ATPCL) encodes a protein involved in glucose homeostasis; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. | Fatty acid synthase 3; Oxidoreductase activity; phosphopantetheine binding; fatty acid synthase activity; hydrolase activity, acting on ester bonds. It is involved in the biological process described with: biosynthetic process. | 0.952 |
| Acsl | ACC | FBpp0305216 | FBpp0087947 | Acyl-CoA synthetase long-chain, isoform J; Long-chain fatty acid-CoA ligase activity; palmitoyl-CoA ligase activity. | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | 0.785 |
| Acsl | CG12170 | FBpp0305216 | FBpp0078358 | Acyl-CoA synthetase long-chain, isoform J; Long-chain fatty acid-CoA ligase activity; palmitoyl-CoA ligase activity. | 3-oxoacyl-[acyl-carrier-protein] synthase activity. It is involved in the biological process described with: fatty acid biosynthetic process; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.532 |
| Acsl | CG3961 | FBpp0305216 | FBpp0074844 | Acyl-CoA synthetase long-chain, isoform J; Long-chain fatty acid-CoA ligase activity; palmitoyl-CoA ligase activity. | LD09909p; Long-chain fatty acid-CoA ligase activity. It is involved in the biological process described with: fatty acid biosynthetic process; long-chain fatty acid metabolic process. | 0.934 |
| Acsl | FASN2 | FBpp0305216 | FBpp0307370 | Acyl-CoA synthetase long-chain, isoform J; Long-chain fatty acid-CoA ligase activity; palmitoyl-CoA ligase activity. | Fatty acid synthase 2 (FASN2) encodes an enzyme required for the synthesis of branched/methylated long chain fatty acids that are the precursors of methylated cuticular hydrocarbons. | 0.936 |
| Acsl | FASN3 | FBpp0305216 | FBpp0297101 | Acyl-CoA synthetase long-chain, isoform J; Long-chain fatty acid-CoA ligase activity; palmitoyl-CoA ligase activity. | Fatty acid synthase 3; Oxidoreductase activity; phosphopantetheine binding; fatty acid synthase activity; hydrolase activity, acting on ester bonds. It is involved in the biological process described with: biosynthetic process. | 0.915 |
| Acsl | beg | FBpp0305216 | FBpp0075038 | Acyl-CoA synthetase long-chain, isoform J; Long-chain fatty acid-CoA ligase activity; palmitoyl-CoA ligase activity. | Probable malonyl-CoA-acyl carrier protein transacylase, mitochondrial; Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the ACP protein. This suggests the existence of the biosynthesis of fatty acids in mitochondria (By similarity). | 0.512 |
| Acsl | bgm | FBpp0305216 | FBpp0080167 | Acyl-CoA synthetase long-chain, isoform J; Long-chain fatty acid-CoA ligase activity; palmitoyl-CoA ligase activity. | Very long-chain-fatty-acid--CoA ligase bubblegum; Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Probably by regulating lipid storage and catabolism, plays a role in neuronal function. | 0.938 |
| Acsl | hll | FBpp0305216 | FBpp0080168 | Acyl-CoA synthetase long-chain, isoform J; Long-chain fatty acid-CoA ligase activity; palmitoyl-CoA ligase activity. | Long-chain-fatty-acid--CoA ligase heimdall; Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Probably by regulating lipid storage and catabolism, plays a role in neuronal function ; Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily. | 0.940 |
| CG12170 | ACC | FBpp0078358 | FBpp0087947 | 3-oxoacyl-[acyl-carrier-protein] synthase activity. It is involved in the biological process described with: fatty acid biosynthetic process; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | 0.882 |