STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG1737FI19420p1. (943 aa)    
Predicted Functional Partners:
CG7692
Uncharacterized protein, isoform A.
   
  
 0.873
CG30403
Uncharacterized protein; DNA binding.
   
  
 0.843
tea
Protein telomere ends associated; Protects telomeres from fusion. Likely to function as a component of the MTV complex along with moi and ver. The complex binds single-stranded DNA in a sequence-independent manner and can protect it from DNA degradation.
   
  
 0.834
CG1815
GH01331p; Methylated histone binding; lysine-acetylated histone binding. It is involved in the biological process described with: regulation of transcription, DNA-templated.
   
  
 0.796
sov
Small ovary, isoform A; Nucleic acid binding.
   
  
 0.733
vers
Versatile (vers) encodes a component of the heterochromatin protein 1 complex that regulates adult testis germline stem cell fate.
   
  
 0.683
HIPP1
HP1 and insulator partner protein 1 (HIPP1) encodes a chromatin-associated protein, displaying strong protein-protein interaction with the product of Su(var)205. It is localized to pericentric heterochromatin, and potentially has a separate role bound to insulators along with the products of su(Hw), mod(mdg4) and Cp190.
   
  
 0.664
Caf1-180
Chromatin assembly factor 1, p180 subunit (Caf1-180) encodes a component of the chromatin assembly factor-1, which couples DNA replication to histone deposition. The product of Caf1-180 is involved in nucleosome organization, DNA endoduplication and double-strand DNA break repair.
   
  
 0.653
E(var)3-9
Enhancer of variegation 3-9; Nucleic acid binding; zinc ion binding. It is involved in the biological process described with: regulation of gene expression; chromatin maintenance.
   
  
 0.645
Odj
LD33778p; DNA binding; zinc ion binding. It is involved in the biological process described with: heterochromatin organization involved in chromatin silencing.
   
  
 0.645
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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