STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG3168LP17136p; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (632 aa)    
Predicted Functional Partners:
LanB2
Laminin B2 (LanB2) encodes a subunit of laminin, a heterotrimeric protein found in the extracellular matrix (ECM) and a major component of the basal lamina. Laminins interact with a variety of cell surface molecules such as integrin receptors and other secreted ECM components. It contributes to ECM organization, tissue adhesion, cell motility and developmental patterning.
     
 0.942
LanB1
LanB1 (LanB1) encodes a subunit of laminin, a heterotrimeric protein found in the extracellular matrix (ECM) and a major component of the basal lamina. Laminins interact with a variety of cell surface molecules such as integrin receptors and other secreted ECM components. It contributes to ECM organization, tissue adhesion, cell motility and developmental patterning.
     
 0.909
LanA
Laminin subunit alpha; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Activates presynaptic signaling involving integrin alpha-PS3/beta-nu and Fak to suppress neuromuscular junction (NMJ) growth during larval development and during low crawling activity, but not during higher-crawling conditions. Mediates, together with integrin alpha-PS3/beta-nu, glutamate receptor-modulated NMJ growth.
     
 0.904
wb
Wing blister (wb) encodes one of 2 laminin alpha chains which assembles into a Laminin molecule. Laminin is an extracellular matrix component that interacts with integrins and mediates cell adhesion, guidance, signalling and basement membrane integrity.
     
 0.904
CG5078
MFS domain-containing protein; Transporter activity. It is involved in the biological process described with: transmembrane transport.
      
 0.642
CG18281
MFS domain-containing protein; Transporter activity. It is involved in the biological process described with: transmembrane transport.
      
 0.640
CG12194
Uncharacterized protein, isoform B; It is involved in the biological process described with: transmembrane transport.
    
 
 0.632
CG32549
Uncharacterized protein, isoform G; 5'-nucleotidase activity.
   
  
 0.621
rtet
Tetracycline resistance; Transporter activity. It is involved in the biological process described with: transmembrane transport.
      
 0.582
CG8036
LP07963p; Transketolase activity; thiamine pyrophosphate binding. It is involved in the biological process described with: regulation of chromatin silencing.
   
  
 0.573
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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