STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG33129AT01533p; It is involved in the biological process described with: response to hyperoxia. (677 aa)    
Predicted Functional Partners:
Sec63
Secretory 63; Protein transmembrane transporter activity; RNA binding. It is involved in the biological process described with: SRP-dependent cotranslational protein targeting to membrane; posttranslational protein targeting to endoplasmic reticulum membrane; posttranslational protein targeting to membrane, translocation.
   
 
 0.711
UGP
UTP--glucose-1-phosphate uridylyltransferase; UGP (UGP) encodes an enzyme involved in hyperoxia response.
      
 0.673
CG42663
MIP12971p; CG42663 encodes a Nck-associated protein 5-like protein involved in determination of lifespan.
      
 0.670
Sec61alpha
Sec61 alpha subunit (Sec61alpha) encodes a subunit of the the translocon, a protein-conducting channel that mediates the co-translational transport of nascent polypeptides into the endoplasmic reticulum. It is a subunit of the Sec61 heterotrimer that forms the core of translocon channel.
   
  
 0.645
CG43340
Uncharacterized protein, isoform M.
      
 0.628
CG7506
Transmembrane protein 70 homolog, mitochondrial; It is involved in the biological process described with: mitochondrial proton-transporting ATP synthase complex assembly.
      
 0.615
CG8841
Uncharacterized protein, isoform A; It is involved in the biological process described with: intracellular protein transport.
      
 0.602
wfs1
Wolframin; Participates in the regulation of cellular Ca(2+) homeostasis, at least partly, by modulating the filling state of the endoplasmic reticulum Ca(2+) store (By similarity). In neurons and glial cells, has a role in maintaining neuronal function and integrity during aging.
      
 0.586
CG1074
SD03208p; Methyltransferase activity; tRNA (guanine-N2-)-methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: methylation.
      
 0.568
fwe
Calcium channel flower; Flower (fwe) encodes a transmembrane protein with different isoforms expressed in 'loser' and in 'winner' cells to mediate win/lose decisions in cell competition and neuronal culling during development and ageing.
   
  
 0.558
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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