STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lmsLateral muscles scarcer, isoform B; Lateral muscles scarcer (lms) encodes a homeodomain transcription factor that is an identity factor for lateral transverse muscles. (378 aa)    
Predicted Functional Partners:
CG17829
EG:115C2.6 protein; Transcription regulatory region sequence-specific DNA binding; transcription coactivator activity; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription, DNA-templated.
    
   0.994
D
Dichaete (D) encodes an HMG-domain protein and member of the Sox family of transcription factors. Its roles include hindgut development, embryonic segmentation, and nervous system development.
   
   0.994
CG14655
GH23506p; Zinc ion binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding. It is involved in the biological process described with: negative regulation of transcription by RNA polymerase II.
    
   0.994
mid
Midline, isoform A; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II activating transcription factor binding; RNA polymerase II regulatory region sequence-specific DNA binding; RNA polymerase II transcription corepressor binding.
   
 
 0.994
CG5674
RH05790p.
    
   0.994
CG14402
AT08210p.
    
   0.994
CG9667
RE31520p; RNA binding. It is involved in the biological process described with: generation of catalytic spliceosome for second transesterification step; mRNA 3'-splice site recognition; mRNA splicing, via spliceosome.
    
   0.994
CG6607
AT25567p; Rab GTPase binding. It is involved in the biological process described with: Rab protein signal transduction.
    
   0.994
Dyb
Dystrobrevin, isoform F; Zinc ion binding; structural constituent of muscle. It is involved in the biological process described with: synaptic signaling.
   
   0.994
CG3085
CG3085 protein; Structural constituent of cytoskeleton. It is involved in the biological process described with: microtubule nucleation; cilium assembly; cilium movement involved in cell motility.
   
   0.994
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.