Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Blm | CG2990 | FBpp0081910 | FBpp0071350 | Bloom syndrome helicase (Blm) encodes a protein that plays important roles in repairing replication fork damage and double-strand breaks. It promotes repair through non-crossover mechanisms, though it also has roles in meiotic recombination. | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | 0.928 |
| Blm | PCNA | FBpp0081910 | FBpp0085619 | Bloom syndrome helicase (Blm) encodes a protein that plays important roles in repairing replication fork damage and double-strand breaks. It promotes repair through non-crossover mechanisms, though it also has roles in meiotic recombination. | Proliferating cell nuclear antigen; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. Belongs to the PCNA family. | 0.813 |
| Blm | PCNA2 | FBpp0081910 | FBpp0080803 | Bloom syndrome helicase (Blm) encodes a protein that plays important roles in repairing replication fork damage and double-strand breaks. It promotes repair through non-crossover mechanisms, though it also has roles in meiotic recombination. | Proliferating cell nuclear antigen 2; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. May function independently of PCNA during DNA repair. | 0.510 |
| Blm | Pif1 | FBpp0081910 | FBpp0309921 | Bloom syndrome helicase (Blm) encodes a protein that plays important roles in repairing replication fork damage and double-strand breaks. It promotes repair through non-crossover mechanisms, though it also has roles in meiotic recombination. | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. | 0.881 |
| Blm | RPA3 | FBpp0081910 | FBpp0310183 | Bloom syndrome helicase (Blm) encodes a protein that plays important roles in repairing replication fork damage and double-strand breaks. It promotes repair through non-crossover mechanisms, though it also has roles in meiotic recombination. | Replication protein A3 (RPA3) encodes a protein involved in the maintenance of the neuronal stem cell population. | 0.993 |
| Blm | RpA-70 | FBpp0081910 | FBpp0081356 | Bloom syndrome helicase (Blm) encodes a protein that plays important roles in repairing replication fork damage and double-strand breaks. It promotes repair through non-crossover mechanisms, though it also has roles in meiotic recombination. | Replication protein A 70 kDa DNA-binding subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.997 |
| Blm | asf1 | FBpp0081910 | FBpp0074715 | Bloom syndrome helicase (Blm) encodes a protein that plays important roles in repairing replication fork damage and double-strand breaks. It promotes repair through non-crossover mechanisms, though it also has roles in meiotic recombination. | Histone chaperone asf1; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Plays a role in the formation of silent heterochromatin. | 0.660 |
| Blm | spn-A | FBpp0081910 | FBpp0084955 | Bloom syndrome helicase (Blm) encodes a protein that plays important roles in repairing replication fork damage and double-strand breaks. It promotes repair through non-crossover mechanisms, though it also has roles in meiotic recombination. | DNA repair protein Rad51 homolog; Spindle A (spn-A) encodes a protein that forms a filament on single-stranded DNA, does a homology search of double-stranded DNA, and catalyzes strand exchange, swapping the single-strand DNA in and displacing the partner of the complementary strand. | 0.992 |
| CG2990 | Blm | FBpp0071350 | FBpp0081910 | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | Bloom syndrome helicase (Blm) encodes a protein that plays important roles in repairing replication fork damage and double-strand breaks. It promotes repair through non-crossover mechanisms, though it also has roles in meiotic recombination. | 0.928 |
| CG2990 | DNApol-alpha73 | FBpp0071350 | FBpp0113035 | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1/p180, an accessory subunit POLA2/p70 and two primase subunits, the catalytic subunit PRIM1/p49 and the regulatory subunit PRIM2/p58) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1 (By similarity). The primase subunit of the polyme [...] | 0.705 |
| CG2990 | Orc5 | FBpp0071350 | FBpp0080120 | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | Origin recognition complex subunit 5; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity). | 0.491 |
| CG2990 | PCNA | FBpp0071350 | FBpp0085619 | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | Proliferating cell nuclear antigen; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. Belongs to the PCNA family. | 0.630 |
| CG2990 | Pif1 | FBpp0071350 | FBpp0309921 | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. | 0.930 |
| CG2990 | RPA3 | FBpp0071350 | FBpp0310183 | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | Replication protein A3 (RPA3) encodes a protein involved in the maintenance of the neuronal stem cell population. | 0.652 |
| CG2990 | RpA-70 | FBpp0071350 | FBpp0081356 | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | Replication protein A 70 kDa DNA-binding subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.971 |
| CG2990 | spn-A | FBpp0071350 | FBpp0084955 | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | DNA repair protein Rad51 homolog; Spindle A (spn-A) encodes a protein that forms a filament on single-stranded DNA, does a homology search of double-stranded DNA, and catalyzes strand exchange, swapping the single-strand DNA in and displacing the partner of the complementary strand. | 0.925 |
| DNApol-alpha73 | CG2990 | FBpp0113035 | FBpp0071350 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1/p180, an accessory subunit POLA2/p70 and two primase subunits, the catalytic subunit PRIM1/p49 and the regulatory subunit PRIM2/p58) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1 (By similarity). The primase subunit of the polyme [...] | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | 0.705 |
| DNApol-alpha73 | Orc5 | FBpp0113035 | FBpp0080120 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1/p180, an accessory subunit POLA2/p70 and two primase subunits, the catalytic subunit PRIM1/p49 and the regulatory subunit PRIM2/p58) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1 (By similarity). The primase subunit of the polyme [...] | Origin recognition complex subunit 5; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity). | 0.745 |
| DNApol-alpha73 | PCNA | FBpp0113035 | FBpp0085619 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1/p180, an accessory subunit POLA2/p70 and two primase subunits, the catalytic subunit PRIM1/p49 and the regulatory subunit PRIM2/p58) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1 (By similarity). The primase subunit of the polyme [...] | Proliferating cell nuclear antigen; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. Belongs to the PCNA family. | 0.902 |
| DNApol-alpha73 | PCNA2 | FBpp0113035 | FBpp0080803 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1/p180, an accessory subunit POLA2/p70 and two primase subunits, the catalytic subunit PRIM1/p49 and the regulatory subunit PRIM2/p58) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1 (By similarity). The primase subunit of the polyme [...] | Proliferating cell nuclear antigen 2; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. May function independently of PCNA during DNA repair. | 0.775 |
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