| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG43658 | Rac1 | FBpp0302018 | FBpp0304252 | Uncharacterized protein, isoform C; Guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: regulation of Rho protein signal transduction; imaginal disc-derived leg morphogenesis; actin cytoskeleton organization; positive regulation of stress fiber assembly; positive regulation of Rho protein signal transduction. | Ras-related protein Rac1; During various developmental processes, regulates changes in cell morphology in response to extracellular signals. During oogenesis, mediates signaling from the tyrosine kinase (RTK) chemoattractant receptors (Egfr and Pvr) to the guidance pathway that control the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Once activating by Pvr and Egfr, promotes the formation of forward-directed actin protrusions which stabilize the DE- cadherin (shg)-mediated adhesions. In turn, DE-mediated adhesion bet [...] | 0.435 |
| CG43658 | RhoGAP16F | FBpp0302018 | FBpp0309969 | Uncharacterized protein, isoform C; Guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: regulation of Rho protein signal transduction; imaginal disc-derived leg morphogenesis; actin cytoskeleton organization; positive regulation of stress fiber assembly; positive regulation of Rho protein signal transduction. | Rho GTPase activating protein at 16F, isoform E; GTPase activator activity. It is involved in the biological process described with: positive regulation of GTPase activity; signal transduction; imaginal disc-derived leg morphogenesis; regulation of GTPase activity. | 0.666 |
| CG43658 | RhoGAP92B | FBpp0302018 | FBpp0310730 | Uncharacterized protein, isoform C; Guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: regulation of Rho protein signal transduction; imaginal disc-derived leg morphogenesis; actin cytoskeleton organization; positive regulation of stress fiber assembly; positive regulation of Rho protein signal transduction. | Rho GTPase-activating protein 92B; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.531 |
| Rac1 | CG43658 | FBpp0304252 | FBpp0302018 | Ras-related protein Rac1; During various developmental processes, regulates changes in cell morphology in response to extracellular signals. During oogenesis, mediates signaling from the tyrosine kinase (RTK) chemoattractant receptors (Egfr and Pvr) to the guidance pathway that control the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Once activating by Pvr and Egfr, promotes the formation of forward-directed actin protrusions which stabilize the DE- cadherin (shg)-mediated adhesions. In turn, DE-mediated adhesion bet [...] | Uncharacterized protein, isoform C; Guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: regulation of Rho protein signal transduction; imaginal disc-derived leg morphogenesis; actin cytoskeleton organization; positive regulation of stress fiber assembly; positive regulation of Rho protein signal transduction. | 0.435 |
| Rac1 | RhoGAP15B | FBpp0304252 | FBpp0288535 | Ras-related protein Rac1; During various developmental processes, regulates changes in cell morphology in response to extracellular signals. During oogenesis, mediates signaling from the tyrosine kinase (RTK) chemoattractant receptors (Egfr and Pvr) to the guidance pathway that control the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Once activating by Pvr and Egfr, promotes the formation of forward-directed actin protrusions which stabilize the DE- cadherin (shg)-mediated adhesions. In turn, DE-mediated adhesion bet [...] | Rho GTPase activating protein at 15B, isoform C; Phosphatidylinositol-3,4,5-trisphosphate binding; GTPase activator activity. It is involved in the biological process described with: positive regulation of GTPase activity; signal transduction; regulation of GTPase activity; imaginal disc-derived leg morphogenesis. | 0.471 |
| Rac1 | RhoGAP16F | FBpp0304252 | FBpp0309969 | Ras-related protein Rac1; During various developmental processes, regulates changes in cell morphology in response to extracellular signals. During oogenesis, mediates signaling from the tyrosine kinase (RTK) chemoattractant receptors (Egfr and Pvr) to the guidance pathway that control the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Once activating by Pvr and Egfr, promotes the formation of forward-directed actin protrusions which stabilize the DE- cadherin (shg)-mediated adhesions. In turn, DE-mediated adhesion bet [...] | Rho GTPase activating protein at 16F, isoform E; GTPase activator activity. It is involved in the biological process described with: positive regulation of GTPase activity; signal transduction; imaginal disc-derived leg morphogenesis; regulation of GTPase activity. | 0.651 |
| Rac1 | RhoGAP54D | FBpp0304252 | FBpp0086058 | Ras-related protein Rac1; During various developmental processes, regulates changes in cell morphology in response to extracellular signals. During oogenesis, mediates signaling from the tyrosine kinase (RTK) chemoattractant receptors (Egfr and Pvr) to the guidance pathway that control the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Once activating by Pvr and Egfr, promotes the formation of forward-directed actin protrusions which stabilize the DE- cadherin (shg)-mediated adhesions. In turn, DE-mediated adhesion bet [...] | Rho GTPase activating protein at 54D, isoform A; GTPase activator activity. It is involved in the biological process described with: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; imaginal disc-derived leg morphogenesis. | 0.461 |
| Rac1 | RhoGAP68F | FBpp0304252 | FBpp0306217 | Ras-related protein Rac1; During various developmental processes, regulates changes in cell morphology in response to extracellular signals. During oogenesis, mediates signaling from the tyrosine kinase (RTK) chemoattractant receptors (Egfr and Pvr) to the guidance pathway that control the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Once activating by Pvr and Egfr, promotes the formation of forward-directed actin protrusions which stabilize the DE- cadherin (shg)-mediated adhesions. In turn, DE-mediated adhesion bet [...] | Rho GTPase activating protein at 68F (RhoGAP68F) encodes a GTPase activating protein acting upon small Rho-family GTPases involved in epithelial morphogenesis. It localizes to Rab4 recycling endosomes, forms a complex with the product of Rab4 and modulates the transport of Rab4 recycling endosomes back to the cell surface. | 0.720 |
| Rac1 | RhoGAP71E | FBpp0304252 | FBpp0288504 | Ras-related protein Rac1; During various developmental processes, regulates changes in cell morphology in response to extracellular signals. During oogenesis, mediates signaling from the tyrosine kinase (RTK) chemoattractant receptors (Egfr and Pvr) to the guidance pathway that control the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Once activating by Pvr and Egfr, promotes the formation of forward-directed actin protrusions which stabilize the DE- cadherin (shg)-mediated adhesions. In turn, DE-mediated adhesion bet [...] | Rho GTPase activating protein at 71E (RhoGAP71E) encodes a Rho GTPase activating protein that is involved in the regulation of actin dynamics during epithelial morphogenesis. | 0.548 |
| Rac1 | RhoGAP92B | FBpp0304252 | FBpp0310730 | Ras-related protein Rac1; During various developmental processes, regulates changes in cell morphology in response to extracellular signals. During oogenesis, mediates signaling from the tyrosine kinase (RTK) chemoattractant receptors (Egfr and Pvr) to the guidance pathway that control the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Once activating by Pvr and Egfr, promotes the formation of forward-directed actin protrusions which stabilize the DE- cadherin (shg)-mediated adhesions. In turn, DE-mediated adhesion bet [...] | Rho GTPase-activating protein 92B; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.468 |
| Rac1 | RhoGAP93B | FBpp0304252 | FBpp0083438 | Ras-related protein Rac1; During various developmental processes, regulates changes in cell morphology in response to extracellular signals. During oogenesis, mediates signaling from the tyrosine kinase (RTK) chemoattractant receptors (Egfr and Pvr) to the guidance pathway that control the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Once activating by Pvr and Egfr, promotes the formation of forward-directed actin protrusions which stabilize the DE- cadherin (shg)-mediated adhesions. In turn, DE-mediated adhesion bet [...] | Rho GTPase activating protein at 93B; GTPase activator activity. It is involved in the biological process described with: positive regulation of GTPase activity; signal transduction; axon guidance; axon midline choice point recognition. | 0.637 |
| Rac1 | RhoGAPp190 | FBpp0304252 | FBpp0305817 | Ras-related protein Rac1; During various developmental processes, regulates changes in cell morphology in response to extracellular signals. During oogenesis, mediates signaling from the tyrosine kinase (RTK) chemoattractant receptors (Egfr and Pvr) to the guidance pathway that control the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Once activating by Pvr and Egfr, promotes the formation of forward-directed actin protrusions which stabilize the DE- cadherin (shg)-mediated adhesions. In turn, DE-mediated adhesion bet [...] | Rho GTPase-activating protein 190; GTPase-activating protein (GAP) for RhoA/Rho1 that plays an essential role in the stability of dorsal branches of mushroom body (MB) neurons. The MB neurons are the center for olfactory learning and memory. Acts by converting RhoA/Rho1 to an inactive GDP-bound state, leading to repress the RhoA/Rho1-Drok-MRLC signaling pathway thereby maintaining axon branch stability. | 0.661 |
| RhoGAP15B | Rac1 | FBpp0288535 | FBpp0304252 | Rho GTPase activating protein at 15B, isoform C; Phosphatidylinositol-3,4,5-trisphosphate binding; GTPase activator activity. It is involved in the biological process described with: positive regulation of GTPase activity; signal transduction; regulation of GTPase activity; imaginal disc-derived leg morphogenesis. | Ras-related protein Rac1; During various developmental processes, regulates changes in cell morphology in response to extracellular signals. During oogenesis, mediates signaling from the tyrosine kinase (RTK) chemoattractant receptors (Egfr and Pvr) to the guidance pathway that control the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Once activating by Pvr and Egfr, promotes the formation of forward-directed actin protrusions which stabilize the DE- cadherin (shg)-mediated adhesions. In turn, DE-mediated adhesion bet [...] | 0.471 |
| RhoGAP15B | RhoGAP16F | FBpp0288535 | FBpp0309969 | Rho GTPase activating protein at 15B, isoform C; Phosphatidylinositol-3,4,5-trisphosphate binding; GTPase activator activity. It is involved in the biological process described with: positive regulation of GTPase activity; signal transduction; regulation of GTPase activity; imaginal disc-derived leg morphogenesis. | Rho GTPase activating protein at 16F, isoform E; GTPase activator activity. It is involved in the biological process described with: positive regulation of GTPase activity; signal transduction; imaginal disc-derived leg morphogenesis; regulation of GTPase activity. | 0.793 |
| RhoGAP15B | RhoGAP54D | FBpp0288535 | FBpp0086058 | Rho GTPase activating protein at 15B, isoform C; Phosphatidylinositol-3,4,5-trisphosphate binding; GTPase activator activity. It is involved in the biological process described with: positive regulation of GTPase activity; signal transduction; regulation of GTPase activity; imaginal disc-derived leg morphogenesis. | Rho GTPase activating protein at 54D, isoform A; GTPase activator activity. It is involved in the biological process described with: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; imaginal disc-derived leg morphogenesis. | 0.574 |
| RhoGAP15B | RhoGAP68F | FBpp0288535 | FBpp0306217 | Rho GTPase activating protein at 15B, isoform C; Phosphatidylinositol-3,4,5-trisphosphate binding; GTPase activator activity. It is involved in the biological process described with: positive regulation of GTPase activity; signal transduction; regulation of GTPase activity; imaginal disc-derived leg morphogenesis. | Rho GTPase activating protein at 68F (RhoGAP68F) encodes a GTPase activating protein acting upon small Rho-family GTPases involved in epithelial morphogenesis. It localizes to Rab4 recycling endosomes, forms a complex with the product of Rab4 and modulates the transport of Rab4 recycling endosomes back to the cell surface. | 0.524 |
| RhoGAP15B | RhoGAP71E | FBpp0288535 | FBpp0288504 | Rho GTPase activating protein at 15B, isoform C; Phosphatidylinositol-3,4,5-trisphosphate binding; GTPase activator activity. It is involved in the biological process described with: positive regulation of GTPase activity; signal transduction; regulation of GTPase activity; imaginal disc-derived leg morphogenesis. | Rho GTPase activating protein at 71E (RhoGAP71E) encodes a Rho GTPase activating protein that is involved in the regulation of actin dynamics during epithelial morphogenesis. | 0.659 |
| RhoGAP15B | RhoGAP92B | FBpp0288535 | FBpp0310730 | Rho GTPase activating protein at 15B, isoform C; Phosphatidylinositol-3,4,5-trisphosphate binding; GTPase activator activity. It is involved in the biological process described with: positive regulation of GTPase activity; signal transduction; regulation of GTPase activity; imaginal disc-derived leg morphogenesis. | Rho GTPase-activating protein 92B; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.580 |
| RhoGAP15B | RhoGAP93B | FBpp0288535 | FBpp0083438 | Rho GTPase activating protein at 15B, isoform C; Phosphatidylinositol-3,4,5-trisphosphate binding; GTPase activator activity. It is involved in the biological process described with: positive regulation of GTPase activity; signal transduction; regulation of GTPase activity; imaginal disc-derived leg morphogenesis. | Rho GTPase activating protein at 93B; GTPase activator activity. It is involved in the biological process described with: positive regulation of GTPase activity; signal transduction; axon guidance; axon midline choice point recognition. | 0.655 |
| RhoGAP15B | RhoGAPp190 | FBpp0288535 | FBpp0305817 | Rho GTPase activating protein at 15B, isoform C; Phosphatidylinositol-3,4,5-trisphosphate binding; GTPase activator activity. It is involved in the biological process described with: positive regulation of GTPase activity; signal transduction; regulation of GTPase activity; imaginal disc-derived leg morphogenesis. | Rho GTPase-activating protein 190; GTPase-activating protein (GAP) for RhoA/Rho1 that plays an essential role in the stability of dorsal branches of mushroom body (MB) neurons. The MB neurons are the center for olfactory learning and memory. Acts by converting RhoA/Rho1 to an inactive GDP-bound state, leading to repress the RhoA/Rho1-Drok-MRLC signaling pathway thereby maintaining axon branch stability. | 0.511 |