STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yellow-bYellow-b, isoform A; Yellow-b (yellow-b) is a member of the multifunctional yellow family of genes that encodes a protein involved in color pattering, eggshell integrity and mating behavior. (453 aa)    
Predicted Functional Partners:
Cpr60D
Cuticular protein 60D, isoform A; Structural constituent of cuticle; structural constituent of chitin-based larval cuticle. It is involved in the biological process described with: chitin-based cuticle development.
   
  
 0.663
ssp7
Short spindle 7; It is involved in the biological process described with: multicellular organism reproduction.
      
 0.608
Cpr65Au
Cuticular protein 65Au, isoform A; Structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development.
      
 0.603
Cpr49Ab
Cuticular protein 49Ab; Structural constituent of cuticle; structural constituent of chitin-based larval cuticle. It is involved in the biological process described with: chitin-based cuticle development.
      
 0.534
lectin-33A
Lectin-33A; Galactose binding; carbohydrate binding.
      
 0.523
rgn
Regeneration, isoform B; DNA-(apurinic or apyrimidinic site) endonuclease activity; carbohydrate binding; DNA N-glycosylase activity. It is involved in the biological process described with: base-excision repair; tissue regeneration.
   
  
 0.514
CG2736
GH15894p; Belongs to the CD36 family.
   
  
 0.497
Mal-A2
Maltase A2; Maltose alpha-glucosidase activity. It is involved in the biological process described with: carbohydrate metabolic process; Belongs to the glycosyl hydrolase 13 family.
      
 0.493
Cyp305a1
Probable cytochrome P450 305a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
     
 0.481
antdh
Antdh; Estradiol 17-beta-dehydrogenase activity; 17-beta-ketosteroid reductase activity; 3-keto sterol reductase activity; oxidoreductase activity; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity. It is involved in the biological process described with: sensory perception of smell; oxidation-reduction process; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.478
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.