STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
CG9643Protein-lysine N-methyltransferase CG9643; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family. (219 aa)    
Predicted Functional Partners:
eEF1alpha2
Elongation factor 1-alpha 2; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
    
 0.815
eEF1alpha1
Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
    
 0.815
CG5013
RE16487p; Methyltransferase activity; protein-lysine N-methyltransferase activity. It is involved in the biological process described with: methylation; peptidyl-lysine trimethylation.
   
  
 0.725
CG17219
FI02048p; S-adenosylmethionine-dependent methyltransferase activity; methyltransferase activity; protein-histidine N-methyltransferase activity. It is involved in the biological process described with: peptidyl-histidine methylation, to form tele-methylhistidine; methylation.
   
  
 0.695
CG9154
Protein-lysine N-methyltransferase CG9154; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
   
  
 0.683
Ntmt
Alpha N-terminal protein methyltransferase 1; Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif (By similarity).
   
  
 0.664
BicD
Protein bicaudal D; This protein is essential for differentiation. It may play a role in localizing of Nanos (a maternal determinant) activity in oocytes. During oogenesis, plays a specific role, together with Rab6 but independently of Sec5, in the polarization of the oocyte microtubule cytoskeleton, in oskar mRNA localization and in the anterodorsal secretion of grk. Plays a role in the biogenesis of annulate lamellae containing nuclear pore complex components.
 
      0.627
CG2614
eEF1A lysine and N-terminal methyltransferase homolog; Dual methyltransferase. It catalyzes N-terminal methylation of target proteins via its C-terminus. It catalyzes dimethylation on lysine residues of target proteins via its N-terminus. Belongs to the methyltransferase superfamily.
   
  
0.617
CG7889
FI07229p; Protein-lysine N-methyltransferase activity; methyltransferase activity. It is involved in the biological process described with: methylation; peptidyl-lysine trimethylation; peptidyl-lysine methylation.
   
  
 0.615
CG9666
LD25448p2; Methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: methylation.
   
  
 0.577
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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