Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG12511 | CG5676 | FBpp0292075 | FBpp0079675 | Uncharacterized protein, isoform B; It is involved in the biological process described with: autophagy of mitochondrion. | RE45833p; It is involved in the biological process described with: autophagy of mitochondrion. | 0.900 |
| CG12511 | Src64B | FBpp0292075 | FBpp0310444 | Uncharacterized protein, isoform B; It is involved in the biological process described with: autophagy of mitochondrion. | Tyrosine-protein kinase Src64B; Src oncogene at 64B (Src64B) encodes a Src family nonreceptor tyrosine kinase. It has many biological roles, including ring canal morphogenesis in oogenesis and the male germline, microfilament ring constriction during cellularization, and modulation of growth and apoptosis. Some of its roles overlap with those of the product of Src42A. | 0.907 |
| CG5676 | CG12511 | FBpp0079675 | FBpp0292075 | RE45833p; It is involved in the biological process described with: autophagy of mitochondrion. | Uncharacterized protein, isoform B; It is involved in the biological process described with: autophagy of mitochondrion. | 0.900 |
| CG5676 | Src64B | FBpp0079675 | FBpp0310444 | RE45833p; It is involved in the biological process described with: autophagy of mitochondrion. | Tyrosine-protein kinase Src64B; Src oncogene at 64B (Src64B) encodes a Src family nonreceptor tyrosine kinase. It has many biological roles, including ring canal morphogenesis in oogenesis and the male germline, microfilament ring constriction during cellularization, and modulation of growth and apoptosis. Some of its roles overlap with those of the product of Src42A. | 0.911 |
| Csk | Dok | FBpp0289007 | FBpp0071008 | C-terminal Src kinase (Csk) encodes a cytoplasmic tyrosine kinase that acts as a tumor suppressor through Src pathway inibition as well as a mediator of the activity of the product of Egfr. | Downstream of kinase (Dok) encodes a membrane-associated protein that functions upstream of the product of Shark to activate Jun kinase signaling during embryonic dorsal closure. | 0.477 |
| Csk | Egfr | FBpp0289007 | FBpp0071571 | C-terminal Src kinase (Csk) encodes a cytoplasmic tyrosine kinase that acts as a tumor suppressor through Src pathway inibition as well as a mediator of the activity of the product of Egfr. | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | 0.874 |
| Csk | Raf | FBpp0289007 | FBpp0310458 | C-terminal Src kinase (Csk) encodes a cytoplasmic tyrosine kinase that acts as a tumor suppressor through Src pathway inibition as well as a mediator of the activity of the product of Egfr. | Raf homolog serine/threonine-protein kinase Raf; Serine/threonine kinase required in the early embryo for the formation of terminal structure. Also required during the proliferation of imaginal cells. May act downstream of Ras85D in the tor signal transduction pathway. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | 0.584 |
| Csk | Ras85D | FBpp0289007 | FBpp0081600 | C-terminal Src kinase (Csk) encodes a cytoplasmic tyrosine kinase that acts as a tumor suppressor through Src pathway inibition as well as a mediator of the activity of the product of Egfr. | Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. | 0.772 |
| Csk | Src64B | FBpp0289007 | FBpp0310444 | C-terminal Src kinase (Csk) encodes a cytoplasmic tyrosine kinase that acts as a tumor suppressor through Src pathway inibition as well as a mediator of the activity of the product of Egfr. | Tyrosine-protein kinase Src64B; Src oncogene at 64B (Src64B) encodes a Src family nonreceptor tyrosine kinase. It has many biological roles, including ring canal morphogenesis in oogenesis and the male germline, microfilament ring constriction during cellularization, and modulation of growth and apoptosis. Some of its roles overlap with those of the product of Src42A. | 0.991 |
| Dok | Csk | FBpp0071008 | FBpp0289007 | Downstream of kinase (Dok) encodes a membrane-associated protein that functions upstream of the product of Shark to activate Jun kinase signaling during embryonic dorsal closure. | C-terminal Src kinase (Csk) encodes a cytoplasmic tyrosine kinase that acts as a tumor suppressor through Src pathway inibition as well as a mediator of the activity of the product of Egfr. | 0.477 |
| Dok | Src64B | FBpp0071008 | FBpp0310444 | Downstream of kinase (Dok) encodes a membrane-associated protein that functions upstream of the product of Shark to activate Jun kinase signaling during embryonic dorsal closure. | Tyrosine-protein kinase Src64B; Src oncogene at 64B (Src64B) encodes a Src family nonreceptor tyrosine kinase. It has many biological roles, including ring canal morphogenesis in oogenesis and the male germline, microfilament ring constriction during cellularization, and modulation of growth and apoptosis. Some of its roles overlap with those of the product of Src42A. | 0.979 |
| Egfr | Csk | FBpp0071571 | FBpp0289007 | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | C-terminal Src kinase (Csk) encodes a cytoplasmic tyrosine kinase that acts as a tumor suppressor through Src pathway inibition as well as a mediator of the activity of the product of Egfr. | 0.874 |
| Egfr | Raf | FBpp0071571 | FBpp0310458 | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | Raf homolog serine/threonine-protein kinase Raf; Serine/threonine kinase required in the early embryo for the formation of terminal structure. Also required during the proliferation of imaginal cells. May act downstream of Ras85D in the tor signal transduction pathway. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | 0.771 |
| Egfr | Ras85D | FBpp0071571 | FBpp0081600 | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. | 0.993 |
| Egfr | Src64B | FBpp0071571 | FBpp0310444 | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | Tyrosine-protein kinase Src64B; Src oncogene at 64B (Src64B) encodes a Src family nonreceptor tyrosine kinase. It has many biological roles, including ring canal morphogenesis in oogenesis and the male germline, microfilament ring constriction during cellularization, and modulation of growth and apoptosis. Some of its roles overlap with those of the product of Src42A. | 0.855 |
| Raf | Csk | FBpp0310458 | FBpp0289007 | Raf homolog serine/threonine-protein kinase Raf; Serine/threonine kinase required in the early embryo for the formation of terminal structure. Also required during the proliferation of imaginal cells. May act downstream of Ras85D in the tor signal transduction pathway. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | C-terminal Src kinase (Csk) encodes a cytoplasmic tyrosine kinase that acts as a tumor suppressor through Src pathway inibition as well as a mediator of the activity of the product of Egfr. | 0.584 |
| Raf | Egfr | FBpp0310458 | FBpp0071571 | Raf homolog serine/threonine-protein kinase Raf; Serine/threonine kinase required in the early embryo for the formation of terminal structure. Also required during the proliferation of imaginal cells. May act downstream of Ras85D in the tor signal transduction pathway. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | 0.771 |
| Raf | Ras85D | FBpp0310458 | FBpp0081600 | Raf homolog serine/threonine-protein kinase Raf; Serine/threonine kinase required in the early embryo for the formation of terminal structure. Also required during the proliferation of imaginal cells. May act downstream of Ras85D in the tor signal transduction pathway. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. | 0.999 |
| Raf | Src64B | FBpp0310458 | FBpp0310444 | Raf homolog serine/threonine-protein kinase Raf; Serine/threonine kinase required in the early embryo for the formation of terminal structure. Also required during the proliferation of imaginal cells. May act downstream of Ras85D in the tor signal transduction pathway. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | Tyrosine-protein kinase Src64B; Src oncogene at 64B (Src64B) encodes a Src family nonreceptor tyrosine kinase. It has many biological roles, including ring canal morphogenesis in oogenesis and the male germline, microfilament ring constriction during cellularization, and modulation of growth and apoptosis. Some of its roles overlap with those of the product of Src42A. | 0.950 |
| Raf | hop | FBpp0310458 | FBpp0073313 | Raf homolog serine/threonine-protein kinase Raf; Serine/threonine kinase required in the early embryo for the formation of terminal structure. Also required during the proliferation of imaginal cells. May act downstream of Ras85D in the tor signal transduction pathway. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | Tyrosine-protein kinase hopscotch; Tyrosine kinase of the non-receptor type, phosphorylates the marelle protein. Required maternally for the establishment of the normal array of embryonic segments: involved in the control of pair- rule gene transcription in a stripe-specific manner. Together with Hsp83 and piwi, mediates canalization, also known as developmental robustness, likely via epigenetic silencing of existing genetic variants and suppression of transposon-induced new genetic variation. | 0.728 |
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