STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG31999RE68558p; Calcium ion binding. It is involved in the biological process described with: extracellular matrix organization. (917 aa)    
Predicted Functional Partners:
CG33978
Uncharacterized protein, isoform C; Calcium ion binding.
   
  
 0.838
Ziz
Zizimin, isoform K; Rho guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: compound eye development; regulation of Rho protein signal transduction; Belongs to the DOCK family.
   
 
 0.795
CG1674
Uncharacterized protein, isoform L; Actin binding. It is involved in the biological process described with: positive regulation of actin filament bundle assembly.
   
  
 0.784
fd102C
Forkhead domain 102C; DNA-binding transcription factor activity, RNA polymerase II-specific; sequence-specific DNA binding. It is involved in the biological process described with: cell differentiation; regulation of transcription by RNA polymerase II; anatomical structure morphogenesis.
    
 
 0.689
Arl4
ADP ribosylation factor-like 4, isoform B; GTP binding. It is involved in the biological process described with: vesicle-mediated transport; intracellular protein transport.
   
 
 0.686
osy
RE14039p; ATP binding; ATPase activity. It is involved in the biological process described with: transmembrane transport.
   
 
 0.620
bin3
Probable RNA methyltransferase bin3; S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it (Probable). Required for dorso-ventral patterning in oogenesis and for anterior-posterior pattern formation during embryogenesis, possibly by binding and stabilizing 7SK RNA, thereby promoting formation of a repressive RNA-protein complex.
      
 0.601
CG14117
RE44251p.
    
 
 0.528
Set
Set (Set) encodes a subunit of the inhibitor of histone acetyltransferase (INHAT) complex, which controls histone acetylation. It is involved in transcriptional regulation, which ultimately controls different processes such as p53-mediated apoptosis and neuronal development.
 
  
   0.514
Mdr49
Multidrug resistance protein homolog 49; Multi drug resistance 49 (Mdr49) encodes drug transmembrane transporter that belongs to the ABCB transporter subfamily and contributes to insecticide resistance.
   
 
 0.500
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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