STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
teqTequila, isoform G; Serine-type endopeptidase activity; chitin binding; scavenger receptor activity; Belongs to the peptidase S1 family. (2792 aa)    
Predicted Functional Partners:
CG18598
FI01460p.
      
 0.669
CG13928
GH11843p; It is involved in the biological process described with: positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; negative regulation of translation.
      
 0.532
Tsp42Ej
Tetraspanin 42Ej (Tsp42Ej) encodes a lysosomal member protein required for the degradation of endocytosed rhodopsin. It prevents light-induced retinal degeneration.
      
 0.532
SmydA-8
SET domain-containing protein SmydA-8, isoform A; Histone deacetylase binding; S-adenosylmethionine-dependent methyltransferase activity. It is involved in the biological process described with: histone lysine methylation; negative regulation of gene expression.
      
 0.523
t
Tan, isoform A; Tan (t) encodes a hydrolase involved in both the conversion of N-beta-alanyldopamine to dopamine in the cuticle and central nervous system, and the conversion of beta-alanylhistamine (carcinine) to histamine in the retina. It functions in vision, cuticular melanization, and neurotransmitter recycling.
      
 0.493
Cpr72Ec
Cuticular protein 72Ec; Structural constituent of eye lens; structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development.
    
 
 0.472
intr
Intrepid; Serine-type endopeptidase activity. It is involved in the biological process described with: sperm storage; proteolysis; negative regulation of female receptivity, post-mating; multicellular organism reproduction.
      
 0.461
aqrs
Aquarius (aqrs) encodes a predicted serine protease produced by the male accessory glands and transferred to females during mating. It is required for the binding of the product of SP to sperm and for the transfer of the products of lectin-46Ca and lectin-46Cb to females during mating.
      
 0.459
Cpn
Calphotin (Cpn) encodes a glutamic acid-rich protein with a strong negative charge and a highly hydrophobic amino acid composition. It functions as an immobile Ca[2+] buffer along the base of the photoreceptor's microvilli. It protects the photoreceptor cells from Ca[2+] overload and light induced degeneration.
    
 
 0.455
CG7220
RH10776p; Ubiquitin-protein transferase activity; ubiquitin conjugating enzyme activity. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; protein monoubiquitination; protein polyubiquitination.
    
 
 0.445
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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