STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOX2Aldehyde oxidase 2 (AOX2) encodes a pyridoxal oxidase involved in pyridoxal metabolism. (1264 aa)    
Predicted Functional Partners:
Uro
Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
  
 
 0.934
DhpD
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. Also has 7,8-dihydropterin deaminase activity, which plays a role in synthesis of the red eye pigment aurodrosopterin.
 
 
 0.931
CG18128
FI08065p; Purine-nucleoside phosphorylase activity. It is involved in the biological process described with: nucleoside metabolic process.
   
 
 0.917
ry
Xanthine dehydrogenase; Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid (By similarity).
  
  
 
0.695
AOX4
Aldehyde oxidase 4 (AOX4) encodes an oxidoreductase that catalyzes the oxidation of pyridoxal to pyridoxate with the release of hydrogen peroxide.
  
 
0.675
AOX1
Aldehyde oxidase 1 (AOX1) encodes a pyridoxal oxidase involved in pyridoxal metabolism.
  
  
0.670
AOX3
Aldehyde oxidase 3 (AOX3) encodes a pyridoxal oxidase involved in pyridoxal metabolism.
  
  
0.663
shop
Probable sulfite oxidase, mitochondrial; Molybdenum ion binding; sulfite oxidase activity; heme binding; molybdopterin cofactor binding. It is involved in the biological process described with: sulfur compound metabolic process; nitrate assimilation; oxidation-reduction process.
      
 0.662
Rlb1
Rlb1 protein; It is involved in the biological process described with: maturation of SSU-rRNA.
      
 0.656
CG12241
LD32196p; GTPase activator activity; Rab GTPase binding. It is involved in the biological process described with: positive regulation of GTPase activity; activation of GTPase activity; intracellular protein transport.
      
 0.604
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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