STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TmcTransmembrane channel-like (Tmc) encodes a protein involved in proprioception and locomotory behavior in larvae. (2036 aa)    
Predicted Functional Partners:
CG15765
GH28601p; Carbohydrate binding. It is involved in the biological process described with: nervous system development.
    
 
 0.845
CG17211
Uncharacterized protein; Integrin binding. It is involved in the biological process described with: epithelial tube morphogenesis.
   
 
 0.835
CG16711
Uncharacterized protein, isoform C.
      
 0.835
CG14120
Uncharacterized protein; It is involved in the biological process described with: apoptotic DNA fragmentation; DNA catabolic process, endonucleolytic.
    
 
 0.691
CG32055
Uncharacterized protein.
    
 
 0.684
mfr
Misfire, isoform F; Misfire (mfr) is a ferlin gene that encodes a protein involved in gamete generation.
   
  
 0.649
Np
Notopleural, isoform A; Serine-type endopeptidase activity; serine-type peptidase activity. It is involved in the biological process described with: proteolysis; liquid clearance, open tracheal system; Belongs to the peptidase S1 family.
   
 
 0.642
Cad99C
Cadherin-99C; Cadherin that functions in epithelial morphogenesis and the intestine epithelial immune response. Essential for female fertility. Regulates the length and organization of apical microvilli in developing follicle cells and salivary glands. Function in the follicle cell is essential for egg development as the microvilli secrete eggshell material such as the vitelline membrane. Acts at least in part by regulating the recruitment of the myosin ck to the follicle cell microvilli. Also required to regulate cell rearrangements during salivary tube elongation, possibly by modulat [...]
      
 0.633
Rift
Riboflavin transmembrane transporter activity. It is involved in the biological process described with: riboflavin transport.
      
 0.631
wfs1
Wolframin; Participates in the regulation of cellular Ca(2+) homeostasis, at least partly, by modulating the filling state of the endoplasmic reticulum Ca(2+) store (By similarity). In neurons and glial cells, has a role in maintaining neuronal function and integrity during aging.
    
 
 0.629
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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